Ghemaxan

Ghemaxan is a medicine that helps prevent blood clots from forming and stops existing clots from growing larger, helping your body break them down.

Form
injektioneste, liuos, esitäytetty ruisku
Strength
4 000 IU (40 mg) / 0.4 ml
Active Ingredient
Enoxaparin sodium
Manufacturer
Chemi S.p.A.

How to Use

Dosage

Your doctor will decide your dose based on your condition and weight, usually ranging from 75 IU (0.75 mg) to 150 IU (1.5 mg) per kilogram, once or twice a day.

Method

This medicine is usually given as an injection under the skin. In some cases, it may also be given into a vein or into a dialysis machine line. Never inject this medicine into a muscle.

Important

Your doctor will determine your maximum daily dose based on your condition.

Possible Side Effects

COMMON
  • Bleeding.
  • Increase in liver enzymes (shown in blood tests).
  • Bruising or pain at the injection site.
  • Bruising more easily than usual (due to low platelet count).
  • Pink spots on the skin, hives, itchy red skin.
  • Headache.
  • Decrease in red blood cells or increase in platelets (shown in blood tests).
RARE
  • Severe allergic reactions, which may include rash, difficulty swallowing or breathing, and swelling of your lips, face, throat, or tongue.
  • Sudden, severe headache, which could be a sign of bleeding in the brain.
  • Tenderness or swelling in the stomach area, which could be a sign of stomach bleeding.
  • Widespread, red, irregular skin changes that may include blisters.
  • Yellowing of the skin or eyes, or dark urine, which could be signs of liver problems.
  • Increase in blood potassium levels (more likely in people with kidney problems or diabetes).
  • Hair loss.
  • Bone thinning (osteoporosis) after long-term use.
  • Tingling, numbness, and muscle weakness (especially in the lower body) after a spinal or epidural injection or lumbar puncture.
  • Loss of bladder or bowel control.
  • Hard lump or swelling at the injection site.

Important Warnings

  • Do not use Ghemaxan if you are allergic to enoxaparin sodium, other heparins, or any other ingredient in this medicine. Signs can include rash, difficulty swallowing or breathing, or swelling of your lips, face, throat, or tongue.
  • Do not use Ghemaxan if you have severe bleeding or a condition that greatly increases your risk of bleeding (such as a stomach ulcer, recent brain or eye surgery, or a stroke caused by brain bleeding).
  • Do not use Ghemaxan if you have had a severe reaction to heparin within the last 100 days that caused a sharp drop in your blood platelet count, or if you have antibodies to enoxaparin in your blood.
  • Do not use Ghemaxan if you are being treated for blood clots and are scheduled for a spinal or epidural injection or a lumbar puncture within the next 24 hours.
  • Seek immediate medical help if you experience a sudden and severe headache, as this could be a sign of bleeding in the brain.
Show 3 more warnings
  • Talk to your doctor right away if you notice any bleeding that won't stop on its own, or signs of heavy bleeding (like unusual weakness, tiredness, paleness, dizziness, headache, or unexplained swelling).
  • Contact your doctor immediately if you experience signs of a new blood clot, such as cramping pain, redness, warmth, or swelling in one leg, or shortness of breath, chest pain, fainting, or coughing up blood.
  • Seek immediate medical help if you develop a painful rash with dark red spots under the skin that do not fade when pressed.

Use in Elderly Patients

Category C

Suitable for older adults, with specific precautions. Reduce the dose in moderately severe renal impairment. Consider potential interactions especially with other drugs that increase the risk of bleeding. (updated 19.9.2025)