Gemcitabin Sun
Gemcitabin SUN is a cancer medicine that works by destroying cancer cells.
Form
infuusioneste, liuos
Strength
10 mg/ml
Active Ingredient
Gemcitabine hydrochloride
Manufacturer
Sun Pharmaceutical Industries Europe B.V.
How to Use
Dosage
Your doctor will calculate your dose based on your body size, usually 1,000–1,250 mg per square meter.
Method
It is given as a drip into a vein (infusion) and takes about 30 minutes.
Important
Your doctor determines the maximum daily dose based on your health and blood tests.
Possible Side Effects
COMMON
- •Rash, itching, or fever
- •Feeling tired, weak, dizzy, or pale (due to low red blood cells)
- •Bleeding from gums, nose, mouth, prolonged bleeding, red urine, or unexpected bruises (due to low platelets)
- •Low white blood cell count (increased infection risk, fever with low white blood cells)
- •Mild breathing difficulties (usually temporary)
- •Nausea, vomiting, diarrhea, constipation, loss of appetite
- •Hair loss
- •Abnormal liver function test results
- •Blood or protein in your urine
- •Mouth sores, pain, redness, or swelling in the mouth
- •Swelling in ankles, fingers, feet, or face
- •Headache, insomnia, or drowsiness
- •Cough, runny nose
- •Sweating
- •Muscle or back pain
- •Infections
RARE
- •Severe breathing problems (e.g., lung scarring, fluid in lungs, wheezing)
- •Irregular heartbeat, heart failure, or heart attack (severe chest pain)
- •Severe kidney or liver failure
- •Stroke
- •Low blood pressure
- •Skin problems like peeling, ulcers, blisters, severe rash, or sunburn-like reaction on previously radiated skin
- •Reactions at the injection site
- •Gangrene of fingers or toes
- •Inflammation of blood vessels
- •Severe allergic reaction (anaphylaxis) with severe rash, swelling (face, lips, tongue), trouble breathing, wheezing, and fast heart rate
- •Generalized swelling, shortness of breath, or weight gain due to fluid leaking from blood vessels into tissues
- •Headache with vision changes, confusion, or seizures
- •Increased platelet count
- •Inflammation of the large intestine or blood clots in small blood vessels
- •Sepsis (bacterial toxins in blood harming organs)
- •Accumulation of eosinophils in the lungs, or skin redness and swelling
Important Warnings
- Do not use if you are allergic to gemcitabine or any other ingredient in this medicine.
- Do not use if you are breastfeeding.
- You will have blood tests before and during treatment to check your kidney and liver function and blood cell counts.
- Tell your doctor if you have had liver, heart, blood vessel, or kidney problems.
- Tell your doctor if you have had or will have radiation therapy.
Show 5 more warnings
- Tell your doctor if you have recently been vaccinated.
- Seek immediate medical help if you develop a severe rash, skin peeling, blisters, or mouth sores.
- This medicine should not be used during pregnancy.
- Male patients should not father children during treatment or for 6 months afterwards; consider sperm banking.
- This medicine may make you drowsy, especially with alcohol. Do not drive or use machines until you know how it affects you.