Fingolimod Orion
Fingolimod Orion is a medicine used to treat multiple sclerosis (MS) to slow down the disease progression and reduce flare-ups.
Form
kapseli, kova
Strength
0.5 mg
Active Ingredient
Fingolimod hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
One 0.5 mg capsule once a day. For children and adolescents weighing over 40 kg, the dose is the same.
Method
Take the capsule by mouth with water once a day. Swallow the capsule whole, do not open it. You can take it with or without food.
Important
Do not take more than one 0.5 mg capsule per day.
Possible Side Effects
COMMON
- •Flu-like symptoms (tiredness, chills, sore throat, joint or muscle pain, fever)
- •Pressure or pain in the cheeks and forehead (sinus infection)
- •Headache
- •Diarrhea
- •Back pain
- •Increased liver enzyme levels in blood tests
- •Cough
- •Herpes virus infection (shingles), causing blisters, burning, itching, or pain on the skin, usually on the upper body or face
- •Slow heart rate (bradycardia) or irregular heartbeat
- •A type of skin cancer called basal cell carcinoma, often appearing as pearl-like bumps
- •Depression and anxiety
- •Weight loss
- •Dizziness
- •Severe headache, often with nausea, vomiting, and sensitivity to light (migraine)
- •Low white blood cell count (lymphocytes, leukocytes)
- •Feeling of weakness
- •Itchy, red, burning rash (eczema)
- •Itching
- •Increased blood fat levels (triglycerides)
- •Hair loss
- •Shortness of breath
- •Blurred vision
- •High blood pressure
- •Muscle pain
- •Joint pain
RARE
- •Pneumonia, with symptoms like fever, cough, and difficulty breathing
- •Macular edema (swelling at the back of the eye, causing shadows or blind spots, blurred vision, or difficulty seeing colors/details)
- •Low platelet count, which increases the risk of bleeding or bruising
- •Melanoma (a type of skin cancer that usually starts from an unusual mole)
- •Seizures (convulsions)
- •Posterior Reversible Encephalopathy Syndrome (PRES), which can cause sudden severe headache, confusion, seizures, and/or vision problems
- •Lymphoma (a type of cancer that affects the lymph system)
- •Squamous cell carcinoma (a type of skin cancer appearing as a firm red lump or a new sore on an existing scar)
- •Abnormal heart electrical activity (T-wave inversion on ECG)
- •Tumor linked to human herpesvirus 8 infection (Kaposi's sarcoma)
- •Allergic reactions, including rash, hives, swelling of lips, tongue, or face
- •Signs of liver disease (including yellowing skin/eyes, nausea, vomiting, right-sided abdominal pain, dark urine, loss of appetite, fatigue, abnormal liver tests)
- •Cryptococcal infections (a type of fungal infection), including meningitis, with symptoms like headache, stiff neck, light sensitivity, nausea, and/or confusion
- •Merkel cell carcinoma (a type of skin cancer that can appear as a skin-colored or reddish-blue, painless lump)
- •Swelling in the hands and feet (peripheral edema)
Important Warnings
- Do not take if your immune system is weak or if you have a serious active or chronic infection (like hepatitis or tuberculosis).
- Do not take if your doctor suspects or has confirmed a rare brain infection called PML.
- Do not take if you have active cancer or severe liver disease.
- Do not take if you have recently had a heart attack, chest pain (angina), stroke, or severe heart failure in the last 6 months, or if you have certain types of irregular heartbeats (arrhythmia) or a long QT interval on an ECG.
- Do not take if you are taking or have recently taken medicines for irregular heartbeats (antiarrhythmics).
Show 2 more warnings
- Do not take if you are pregnant or could become pregnant and are not using effective birth control.
- Do not take if you are allergic to fingolimod or any other ingredient in this medicine.