Ferulinor
Ferulinor contains lenalidomide, a medicine that helps your immune system fight certain cancers like multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.
Form
kapseli, kova
Strength
2.5 mg
Active Ingredient
Lenalidomide
Manufacturer
STADA Nordic ApS
How to Use
Dosage
Your doctor will tell you exactly how much Ferulinor to take, as it varies for each person.
Method
Swallow the capsules whole with water, do not break or chew them. You can take them with or without food, at the same time each day, as directed by your doctor.
Important
Your doctor will determine your daily dose and the duration of your treatment cycle, which can be 21 or 28 days.
Possible Side Effects
COMMON
- •Decreased red blood cells, which can cause anemia leading to tiredness and weakness
- •Rashes, itching
- •Muscle cramps, muscle weakness, muscle and joint pain, bone pain, back pain, limb pain
- •General swelling, including swelling in arms and legs
- •Weakness, fatigue
- •Fever and flu-like symptoms, including fever, muscle aches, headache, earache, cough, and chills
- •Numbness, tingling or burning sensation on the skin, pain in hands or feet, dizziness, tremors
- •Decreased appetite, altered taste
- •Increased pain, increased tumor size or redness around the tumor
- •Weight loss
- •Constipation, diarrhea, nausea, vomiting, stomach pain, heartburn
- •Low levels of potassium, calcium, and/or sodium in the blood
- •Underactive thyroid
- •Leg pain (possibly a symptom of a blood clot), chest pain or shortness of breath (possibly a symptom of a blood clot in the lungs, i.e., pulmonary embolism)
- •All types of infections, including sinus infections, lung infections, and upper respiratory tract infections
- •Shortness of breath
- •Blurred or weak vision
- •Clouding of the eye (cataract)
- •Kidney problems
- •Abnormal liver test results, increased liver enzyme levels
- •Changes in blood protein that can cause blood vessel swelling (vasculitis)
- •High blood sugar (diabetes), low blood sugar
- •Headache
- •Nosebleed
- •Dry skin
- •Depression, mood changes, sleep difficulties
- •Cough
- •Low blood pressure
- •General discomfort, malaise
- •Sore, inflamed mouth, dry mouth
- •Dehydration
RARE
- •Destruction of red blood cells (hemolytic anemia)
- •Certain types of skin cancers
- •Bleeding from gums, stomach, or intestines
- •High blood pressure, slow, fast, or irregular heart rate
- •Increased amount of a substance released during normal and abnormal breakdown of red blood cells
- •Increased levels of a protein indicating inflammation in the body
- •Skin darkening, subcutaneous bleeding (usually bruising), skin discoloration due to hemorrhage, skin swelling due to hemorrhage, bruising, skin reactions, red skin, cracked skin, scaly or peeling skin, hives
- •Increased uric acid levels in the blood
- •Increased sweating, night sweats
- •Difficulty swallowing, sore throat, difficulty producing sound or voice changes
- •Nasal discharge
- •Unusually high or low urine output or inability to control urination, blood in urine
- •Shortness of breath, especially when lying down (which may be a symptom of heart failure)
- •Erectile dysfunction
- •Stroke, fainting, vertigo (inner ear disorder causing a sensation of spinning), temporary loss of consciousness
- •Chest pain radiating to arms, neck, jaw, back or stomach, sweating, shortness of breath, nausea or vomiting (symptoms of a heart attack)
- •Muscle weakness, lack of energy
- •Neck pain, chest pain
- •Chills
- •Joint swelling
- •Slowed or blocked bile flow from the liver
- •Low phosphate or magnesium levels in the blood
- •Speech difficulties
- •Liver damage
- •Balance problems, difficulty moving
- •Deafness, ringing in ears (tinnitus)
- •Nerve pain, unpleasant, abnormal sensations, especially to touch
- •Excess iron in the body
- •Thirst
- •Confusion
- •Toothache
- •Falls, which can lead to injury
- •Bleeding inside the skull
- •Circulatory problems
- •Vision loss
- •Decreased sex drive (libido)
- •Large urine production with bone pain and weakness, which can be symptoms of a kidney disease (Fanconi syndrome)
- •Yellowing of skin, mucous membranes or eyes (jaundice), light stools, dark urine, itching, rash, stomach pain or bloating – these may be symptoms of liver damage (liver failure)
- •Stomach pain, bloating or diarrhea, which can be symptoms of colon inflammation (colitis or appendicitis)
- •Kidney cell damage (renal tubular necrosis)
- •Skin discoloration, sensitivity to sunlight
- •Tumor lysis syndrome – metabolic complications that can occur during cancer treatment, where dying cancer cells release substances that cause blood chemistry changes (like high potassium, phosphorus, uric acid, low calcium), potentially leading to kidney and heart problems, seizures, and sometimes death
- •High blood pressure in the blood vessels supplying the lungs (pulmonary hypertension)
- •Sudden or mild but worsening upper abdominal and/or back pain that lasts for several days, possibly accompanied by nausea, vomiting, fever, and rapid heartbeat. These symptoms may be caused by pancreatitis.
- •Wheezing, shortness of breath or dry cough, which may be symptoms of lung tissue inflammation
- •Muscle tissue breakdown (muscle pain, weakness or swelling) which can cause kidney problems (rhabdomyolysis) has been observed in rare cases, some of which occurred when lenalidomide was given with a statin (a cholesterol-lowering drug)
- •Skin disease caused by inflammation of small blood vessels, associated with joint pain and fever (leukocytoclastic vasculitis)
- •Rupture of the stomach or intestinal wall. This can lead to a very serious infection. Tell your doctor if you experience severe abdominal pain, fever, nausea, vomiting, bloody stools, or changes in bowel habits.
- •Viral infections, including shingles (a viral infection causing a painful blistering rash) and reactivation of hepatitis B infection (which can cause yellowing of the skin and eyes, dark brown urine, right-sided abdominal pain, fever, nausea, or vomiting)
- •Rejection of solid organ transplants (such as kidney, heart)
Important Warnings
- Do not take Ferulinor if you are pregnant, planning to become pregnant, or suspect you might be pregnant, as it can harm the unborn baby. Do not take if you are allergic to lenalidomide or any other ingredients.
- Tell your doctor if you have had blood clots before; Ferulinor can increase your risk of developing new clots.
- Inform your doctor if you have symptoms of an infection (like cough or fever) or a history of viral infections (like hepatitis B, shingles, or HIV), as Ferulinor may reactivate them.
- Tell your doctor if you have kidney problems, heart issues (like a heart attack or high blood pressure), or high cholesterol.
- Seek immediate medical attention if you experience severe allergic reactions (hives, rash, swelling of face/mouth, difficulty breathing) or widespread skin reactions with fever, flu-like symptoms, or swollen lymph nodes (DRESS syndrome).
Show 6 more warnings
- Contact your doctor immediately if you notice changes in vision, speech, walking, balance, numbness, memory, or confusion, as these could be signs of a serious brain condition (PML).
- Report any new or worsening shortness of breath, tiredness, dizziness, chest pain, fast heartbeat, or swelling in your legs/ankles to your doctor immediately, as these could indicate a serious lung condition.
- Do not donate blood during treatment or for at least 7 days after stopping Ferulinor.
- Avoid driving or operating machinery if you feel dizzy, tired, sleepy, or have blurred vision after taking Ferulinor.
- Ferulinor contains lactose; tell your doctor if you have sugar intolerance. It is also nearly sodium-free.
- Pregnant women should not handle these capsules. Caregivers should wear disposable gloves when handling the capsules to avoid direct contact and then wash their hands thoroughly.