These patches help relieve very strong and long-lasting pain for adults and children over 2 years old who are already on opioid medicine.
Apply one patch every three days (72 hours), unless your doctor tells you otherwise.
Apply the patch to a flat, clean, dry, and cool area of your upper body or arm. For children, always apply to the upper back to prevent removal. Remove the old patch before applying a new one at the same time of day, every three days.
Do not apply more than one patch at a time, and do not change it more often than every three days (72 hours), unless directed by your doctor.
Avoid use in older adults. Sedative. Serotonergic. Intended for the treatment of cancer pain. Not suitable for initiating opioid medication. Low transdermal efficacy in cachectic patients. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential significant interactions. (updated 24.3.2025)