Feiba
Feiba is a medicine made from human plasma that helps blood clot, even if you have low or missing clotting factors.
Form
infuusiokuiva-aine ja liuotin, liuosta varten
Strength
100 U/ml
Active Ingredient
Factor VIII inhibitor bypassing activity
Manufacturer
Baxalta Innovations GmbH
How to Use
Dosage
Your doctor will decide your dose, usually 50-100 units of Feiba per kg of body weight.
Method
Feiba is given slowly into a vein after the powder is dissolved with the provided liquid, at an infusion rate of 2-10 units per kg of body weight per minute.
Important
Do not exceed 200 units of Feiba per kg of body weight per day.
Possible Side Effects
COMMON
- •Hypersensitivity
- •Headache
- •Dizziness
- •Low blood pressure
- •Rash
- •Positive hepatitis B surface antigen test
RARE
- •Fibrin depletion syndrome (DIC), a severe blood clotting disorder
- •Increased inhibitor titer
- •Anaphylactic reactions
- •Hives all over the body
- •Numbness in limbs
- •Abnormal or decreased sensation
- •Stroke (thrombotic stroke, embolic stroke)
- •Drowsiness
- •Altered taste
- •Heart attack (myocardial infarction)
- •Rapid heart rate (tachycardia)
- •Blood clot formation that travels in blood vessels (thromboembolic events, venous or arterial thrombosis)
- •Increased blood pressure
- •Redness
- •Pulmonary embolism (lung blood clot)
- •Airway constriction (bronchospasm)
- •Wheezing
- •Cough
- •Shortness of breath
- •Vomiting
- •Diarrhea
- •Abdominal pain
- •Nausea
- •Facial numbness
- •Swelling of face, tongue, and lips (angioedema)
- •Itching
- •Pain at injection site
- •General malaise
- •Feeling of warmth (hot flush)
- •Chills
- •Fever
- •Chest pain
- •Chest discomfort
- •Blood pressure decrease
- •Increased fibrin D-dimer in blood
- •Stinging pain or numbness in the face, arms or legs, and a drop in blood pressure (with rapid infusion)
Important Warnings
- Do not use Feiba if you are allergic to the active substance or any other ingredient.
- Do not use Feiba if you have disseminated intravascular coagulation (DIC), a severe blood clotting disorder.
- If you have had a heart attack, blood vessel blockage, or blood clot, Feiba should only be used for life-threatening bleeding.
- If you experience symptoms like skin redness, rash, itching, swelling of lips or tongue, breathing difficulties, chest tightness, malaise, dizziness, or a drop in blood pressure, stop the infusion immediately and contact your doctor.
- If your blood pressure or heart rate changes strongly, or you have breathing difficulties, cough, or chest pain, stop the infusion immediately and contact your doctor.
Show 3 more warnings
- Concomitant use with recombinant Factor VIIa (rFVIIa) may increase the risk of blood clots.
- Do not use the product if the package or sterile seal is damaged, or if the solution is cloudy or contains particles.
- Do not store in the refrigerator after reconstitution; use the solution within three hours.