Ezetimib/Atorvastatin Krka
This medicine helps lower high cholesterol and fats in your blood and increases good cholesterol.
Form
tabletti, kalvopäällysteinen
Strength
10 mg / 10 mg
Active Ingredient
Ezetimibe
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
One tablet once a day.
Method
Take the tablet whole with water, with or without food. Do not divide the tablet.
Important
The maximum daily dose is one tablet.
Possible Side Effects
COMMON
- •Diarrhea
- •Muscle aches
RARE
- •Flu-like symptoms
- •Depression
- •Difficulty sleeping, sleep problems
- •Dizziness
- •Headache
- •Tingling sensation
- •Slow heartbeat
- •Hot flashes
- •Shortness of breath
- •Stomach pain
- •Bloating
- •Constipation
- •Indigestion
- •Gas
- •Frequent bowel movements
- •Stomach inflammation
- •Nausea
- •Abdominal discomfort
- •Acne
- •Hives
- •Joint pain
- •Back pain
- •Leg cramps
- •Muscle fatigue, cramps or weakness
- •Pain in hands and feet
- •Unusual weakness, tiredness or feeling unwell
- •Swelling especially in the ankles (edema)
- •Increase in certain blood values indicating muscle or liver function (CK, creatine kinase)
- •Weight gain
- •Myasthenia gravis (general muscle weakness, sometimes affecting breathing muscles)
- •Ocular myasthenia (eye muscle weakness)
- •Severe allergic reaction with swelling of face, lips, tongue, and/or throat, which may cause breathing or swallowing difficulties (requires immediate treatment)
- •Raised red, sometimes target-like rashes
- •Liver problems
- •Cough
- •Heartburn
- •Decreased or loss of appetite
- •High blood pressure
- •Rash and itching
- •Tendon injury
- •Gallstones or gallbladder inflammation (which can cause abdominal pain, nausea, vomiting)
- •Pancreatitis (inflammation of the pancreas), often with severe abdominal pain
- •Decreased blood cell count, which can cause bruising or bleeding
- •Nasal inflammation, nosebleeds
- •Neck pain, chest pain, sore throat
- •Increased and decreased blood sugar levels (if you have diabetes, carefully monitor your blood sugar levels)
- •Nightmares
- •Numbness or tingling in fingers and toes
- •Decreased sense of pain or touch
- •Taste changes, dry mouth
- •Memory loss
- •Ringing in ears and/or head, hearing loss
- •Vomiting
- •Belching
- •Hair loss
- •Fever
- •Positive white blood cell test in urine
- •Blurred vision, visual disturbances
- •Gynecomastia (male breast enlargement)
- •Sexual difficulties
- •Breathing problems (including persistent cough and/or shortness of breath or fever)
- •Diabetes (new onset or worsening, more likely if you have high blood sugar, high fat levels, are overweight, or have high blood pressure)
- •Persistent muscle pain, tenderness, or weakness after stopping the medicine (may not disappear)
- •Severe skin reactions with peeling and swelling, blisters on skin, mouth, eyes, and genitals, and fever. Rash with pink-red patches, especially on palms or soles, which may burst. (Lupus-like syndrome)
- •Muscle weakness, tenderness, pain, rupture, or reddish-brown discoloration of the urine, especially if you feel unwell or have a high fever. This can be due to abnormal muscle breakdown (rhabdomyolysis), which can be life-threatening and lead to kidney problems.
- •Unexpected or unusual bleeding or bruising (may indicate liver problems)
Important Warnings
- Do not take if you are allergic to ezetimibe, atorvastatin, or any other ingredients.
- Do not take if you have or have had liver disease, or if your liver blood tests are abnormal.
- Do not take if you are pregnant, trying to get pregnant, breastfeeding, or could become pregnant and are not using reliable birth control.
- Do not take if you are using glecaprevir/pibrentasvir for Hepatitis C.
- Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if you also feel unwell or have a fever. This could be a sign of a serious muscle condition.
Show 3 more warnings
- If you need to take fusidic acid for a bacterial infection, you must temporarily stop taking this medicine. Your doctor will tell you when it is safe to restart.
- Tell your doctor if you have myasthenia (general muscle weakness) or ocular myasthenia (eye muscle weakness), as statins can sometimes worsen these conditions or cause them to appear.
- Discuss with your doctor if you have kidney problems, an underactive thyroid (hypothyroidism), a history of muscle problems with other cholesterol-lowering medicines, or if you regularly drink a lot of alcohol.