Everolimus Avansor
Everolimus Avansor is a cancer medicine that reduces blood flow to tumors and slows down cancer cell growth and spread.
Form
tabletti
Strength
5 mg
Active Ingredient
Everolimus
Manufacturer
Avansor Pharma Oy
How to Use
Dosage
The recommended dose is 10 mg once a day.
Method
Take Everolimus Avansor once a day around the same time, with or without food. Swallow the tablets whole with a glass of water; do not chew or crush them.
Important
The maximum recommended daily dose is 10 mg.
Possible Side Effects
COMMON
- •Increased body temperature, chills (signs of infection)
- •Fever, cough, difficulty breathing, wheezing (signs of lung inflammation, i.e., pneumonia)
- •Tiredness, shortness of breath, dizziness, pale skin (signs of low red blood cells, anemia)
- •High blood sugar levels (hyperglycemia)
- •Loss of appetite, high blood fat levels (hypercholesterolemia)
- •Taste disturbances (dysgeusia), headache
- •Nosebleeds (epistaxis)
- •Cough
- •Mouth sores
- •Stomach problems including nausea or diarrhea
- •Rash
- •Itching
- •Feeling weak or tired, swelling of arms, hands, feet, ankles, or other body parts (signs of edema)
- •Weight loss
RARE
- •Excessive thirst, increased urine output, increased appetite with weight loss, tiredness (signs of diabetes)
- •Bleeding, for example in the intestines
- •Significantly reduced urine output (sign of kidney failure)
- •Fever, rash, joint pain and inflammation, tiredness, loss of appetite, nausea, yellow skin (jaundice), pain in the upper right abdomen, pale stools, dark urine (signs of reactivated Hepatitis B)
- •Shortness of breath, difficulty breathing when lying down, swelling of legs and feet (signs of heart failure)
- •Swelling and/or pain in one leg, usually the calf, redness or warmth in that area of the skin (signs of a blocked blood vessel (vein) in the leg due to blood clotting)
- •Spontaneous bleeding and bruising (signs of low platelet count, i.e. thrombocytopenia), fever, sore throat due to infection or mouth sores (signs of low white blood cells, leukopenia, lymphopenia and/or neutropenia)
- •Shortness of breath (dyspnea)
- •Thirst, low urine output, dark urine, dry, red skin, irritability (signs of dehydration)
- •Sleep difficulties (insomnia)
- •Headache, dizziness (signs of high blood pressure, i.e., hypertension)
- •Swelling of a part or whole arm (including fingers) or leg (including toes), feeling of heaviness, limited movement, discomfort (possible signs of lymph circulation disorders)
- •Fever
- •Inflammation inside the mouth, stomach, or intestines
- •Dry mouth
- •Heartburn (dyspepsia)
- •Nausea (vomiting)
- •Difficulty swallowing (dysphalgia)
- •Abdominal pain
- •Acne
- •Rash and pain in palms and soles of feet (hand-foot syndrome)
- •Skin redness (erythema)
- •Joint pain
- •Mouth pain
- •Menstrual disorders, such as irregular periods
- •Elevated blood lipid levels (hyperlipidemia, elevated triglycerides)
- •Low potassium level in blood (hypokalemia)
- •Low phosphate level in blood (hypophosphatemia)
- •Low calcium level in blood (hypocalcemia)
- •Dry skin, flaky skin, skin damage
- •Nail damage, brittle nails
- •Slight hair loss
- •Abnormal liver function test results (increased levels of alanine and aspartate aminotransferase)
- •Abnormal kidney function test results (increased creatinine levels)
- •Eyelid swelling
- •Protein in urine
- •Feeling weak, spontaneous bleeding and bruising, and frequent infections with symptoms like fever, chills, sore throat, or mouth sores (signs of low blood cell count, i.e., pancytopenia)
- •Loss of taste (ageusia)
- •Coughing up blood (hemoptysis)
- •Menstrual disorders, such as missed periods (amenorrhea)
- •Urinating more often than usual during the day
- •Chest pain
- •Abnormal wound healing
- •Hot flashes
- •Watery, itchy, and red eyes, eye redness or bloodshot eyes (conjunctivitis)
- •Tiredness, shortness of breath, dizziness, pale skin (signs of low red blood cell count, possibly due to a type of anemia called pure red cell aplasia)
- •Swelling of the face around the eyes and mouth, inside the mouth and/or throat, and tongue, difficulty breathing and swallowing (angioedema), these can be signs of an allergic reaction.
- •Reaction in a previously radiated area, e.g., skin redness or lung inflammation (so-called radiation recall syndrome)
- •Worsening of radiation therapy side effects
Important Warnings
- Do not take if you are allergic to everolimus, similar medicines like sirolimus or temsirolimus, or any other ingredient in this medicine.
- Tell your doctor if you have liver problems, as your dose may need to be adjusted.
- This medicine can increase blood sugar levels, especially if you have diabetes.
- Avoid live vaccines while taking this medicine.
- This medicine can increase cholesterol and other fat levels in your blood.
Show 13 more warnings
- Tell your doctor if you recently had surgery or have wounds that haven't healed, as this medicine can slow healing.
- Inform your doctor if you have an infection, as it may need to be treated before starting this medicine.
- Tell your doctor if you have ever had Hepatitis B, as it might become active again.
- Inform your doctor if you have received or will receive radiation therapy, as this medicine can worsen radiation side effects.
- This medicine can weaken your immune system, making you more prone to infections.
- This medicine can affect your kidney function. Your doctor will monitor your kidneys.
- This medicine can cause shortness of breath, cough, and fever.
- This medicine can cause mouth sores.
- Do not eat grapefruit or drink grapefruit juice while taking this medicine.
- Do not give this medicine to children or adolescents under 18 years of age.
- This medicine is not recommended during pregnancy as it may harm the unborn baby.
- Do not breastfeed during treatment or for 2 weeks after your last dose, as it may harm your baby.
- If you feel unusually tired, be extra careful when driving or using machines.