Etoposide Accord
Etoposide Accord is a medicine used to treat various types of cancer by stopping cancer cells from growing.
Form
infuusiokonsentraatti, liuosta varten
Strength
20 mg/ml
Active Ingredient
Etoposide
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will decide your exact dose, which is usually given for 2 to 5 days. For adults, this is typically 50-120 mg per square meter of body surface area. For children, it's typically 75-150 mg per square meter of body surface area.
Method
A healthcare professional will give you this medicine as a slow drip into a vein (infusion). This usually takes 30 to 60 minutes.
Important
Your doctor will determine your maximum daily dose. Do not exceed the dose your doctor prescribes.
Possible Side Effects
COMMON
- •Blood problems (your doctor will check with blood tests)
- •Feeling sick (nausea) and throwing up (vomiting)
- •Loss of appetite
- •Stomach pain
- •Constipation
- •Temporary hair loss
- •Liver damage
- •Increased liver enzyme levels
- •Changes in skin color
- •Yellowing of skin or eyes (jaundice)
- •Feeling weak or tired
- •Generally feeling unwell
- •Dizziness
- •High blood pressure
- •Low blood pressure
- •Soreness in your lips, mouth, or throat
- •Redness of the skin
- •Infections (including serious ones like lung infections)
- •Diarrhea
- •Skin problems like rash or itching
- •Inflammation in your veins
- •Reactions at the injection site (where the medicine is given)
RARE
- •Tingling or numbness in your hands and feet
- •Bleeding
- •Seizures
- •Feeling very sleepy or tired
- •Changes in taste
- •Difficulty swallowing
- •Severe skin reactions, including painful blisters, fever, or skin peeling (like Stevens-Johnson syndrome)
- •Severe sunburn-like rash, especially on skin that was previously treated with radiation
- •Fever
- •Temporary loss of sight
- •Breathing difficulties
- •Heartburn (reflux disease)
- •Redness of face and neck (flushing)
- •A serious blood cancer (acute leukemia)
- •Irregular heartbeat or heart attack
- •Infertility
- •Sudden kidney failure
Important Warnings
- Do not take if you are allergic to etoposide or any other ingredients in this medicine.
- Do not take if you have recently received a live vaccine, including the yellow fever vaccine.
- Do not breastfeed while using this medicine.
- Tell your doctor or nurse right away if you notice any signs of a severe allergic reaction, such as swelling of your throat or tongue, trouble breathing, fast heartbeat, or skin rash.
- Do not use during pregnancy unless your doctor says it is absolutely necessary.
Show 4 more warnings
- Both men and women must use effective birth control during treatment and for at least 6 months after the last dose. Men should not father a child during this time.
- This medicine can lower your blood cell counts, making you more likely to get infections or bleed easily. Your doctor will take blood tests to check this.
- Tell your doctor if you have liver or kidney problems, infections, or have recently had radiation or chemotherapy, as this medicine can affect these conditions and cause serious issues like tumor lysis syndrome.
- This medicine can make you feel tired, sick, or dizzy. Do not drive or use machines until you know how it affects you and have talked to your doctor.