Etoposid Fresenius Kabi
Etoposide is a cancer medicine used to treat certain types of cancer in adults and children.
Form
infuusiokonsentraatti, liuosta varten
Strength
20 mg/ml
Active Ingredient
Etoposide
Manufacturer
Fresenius Kabi AB
How to Use
Dosage
Your doctor will determine your dose individually. For adults, typically 50-100 mg/m² of body surface area daily for 5 consecutive days OR 100–120 mg/m² on days 1, 3, and 5. For children with blood cancer or lymphoma, the dose is 75–150 mg/m² daily for 2–5 days.
Method
A doctor or nurse will give this medicine to you as a slow drip (infusion) into a vein, which takes 30-60 minutes.
Important
Your doctor will determine the maximum dose individually. Treatment courses can be repeated no sooner than 21 days after the first course.
Possible Side Effects
COMMON
- •Changes in blood cell counts (requires blood tests)
- •Temporary hair loss
- •Nausea and vomiting
- •Abdominal pain
- •Loss of appetite
- •Skin discoloration (pigmentation changes)
- •Constipation
- •Weakness and general feeling of unwellness
- •Liver damage or increased liver enzyme values
- •Jaundice (yellowing of skin and eyes)
- •Acute leukemia (rarely)
- •Irregular heartbeat or heart attack (rarely)
- •Dizziness
- •Diarrhea
- •Reactions at the infusion site
- •Allergic reactions
- •High or low blood pressure
- •Sore ulcers on lips, mouth, or throat
- •Skin problems like itching and rash
- •Vein inflammation
- •Infections (especially in patients with weakened immune systems)
RARE
- •Tingling or numbness in hands and feet
- •Bleeding
- •Acid reflux
- •Skin redness
- •Difficulty swallowing
- •Change in taste
- •Convulsions (seizures)
- •Fever
- •Drowsiness or fatigue
- •Difficulty breathing
- •Temporary blindness
- •Severe skin reactions, such as painful blisters, fever, and skin peeling (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- •Sunburn-like rash on previously radiated skin (radiation recall dermatitis)
- •Tumor lysis syndrome (problems caused by the breakdown of cancer cells)
- •Swelling of face and tongue
- •Infertility
Important Warnings
- Do not use Etoposide if you are allergic to etoposide or any other ingredient in this medicine.
- Do not use this medicine if you are breastfeeding or planning to breastfeed.
- Do not use Etoposide if you have recently received a live vaccine, including the yellow fever vaccine.
- Tell your doctor if you have low albumin levels in your blood, have recently had radiation or chemotherapy, have an infection, or have liver or kidney problems.
- This medicine can lower your blood cell counts, increasing your risk of infection and bleeding. You will have regular blood tests to monitor this.
Show 6 more warnings
- During pregnancy, Etoposide should only be used if your doctor considers it absolutely necessary.
- Both men and women must use effective birth control during treatment and for at least 6 months after treatment ends.
- If you feel tired, sick, dizzy, or faint, do not drive or use machines until you have discussed this with your doctor.
- This medicine contains alcohol, which can cause drowsiness and affect your ability to drive or use machines, especially in children.
- Tell your doctor if you have epilepsy or liver problems, as this medicine contains alcohol and benzyl alcohol.
- This medicine contains benzyl alcohol, which can cause allergic reactions. High amounts can build up in the body and cause problems, especially in children under 3 years old and newborns.