Estrofem
Estrofem is a hormone replacement therapy containing estradiol, used to relieve menopause symptoms and prevent osteoporosis in women who cannot use other medicines for this purpose.
Form
tabletti, kalvopäällysteinen
Strength
2 mg
Active Ingredient
Estradiol hemihydrate
Manufacturer
Novo Nordisk A/S
How to Use
Dosage
Take one tablet every day.
Method
Take the tablet at approximately the same time each day. After finishing one 28-day pack, start a new pack immediately.
Important
One tablet per day.
Possible Side Effects
COMMON
- •Depression
- •Headache
- •Abdominal pain
- •Nausea
- •Leg cramps
- •Breast pain, tenderness or enlargement
- •Swelling (fluid retention)
- •Weight gain
RARE
- •Allergic reaction (hypersensitivity) with symptoms like hives, itching, swelling, difficulty breathing, low blood pressure.
- •Vision disturbances
- •Blood clots in veins (venous thromboembolism)
- •Heartburn (indigestion)
- •Vomiting
- •Flatulence or feeling of bloating in the abdomen
- •Gallstones
- •Itching or hives (urticaria)
- •Irregular vaginal bleeding
- •Worsening of migraine
- •Stroke
- •Insomnia
- •Epilepsy
- •Changes in sex drive
- •Vaginal yeast infection
- •Worsening of asthma
- •Dizziness
- •Diarrhea
- •Hair loss (alopecia)
- •High blood pressure
Important Warnings
- Do not take Estrofem if you have or have had breast cancer or any estrogen-sensitive cancer.
- Do not take Estrofem if you have unexplained vaginal bleeding or untreated thickening of the womb lining.
- Do not take Estrofem if you have or have had blood clots in a vein (e.g., in legs or lungs) or a blood clotting disorder.
- Do not take Estrofem if you have had a heart attack, stroke, or angina.
- Do not take Estrofem if you have liver disease and your liver test results are still abnormal.
Show 2 more warnings
- Stop taking Estrofem and contact your doctor immediately if you become pregnant.
- Stop taking Estrofem and contact your doctor immediately if you notice yellowing of your skin or eyes, swelling of your face/tongue/throat with breathing difficulties, a significant increase in blood pressure, or symptoms of a blood clot (e.g., painful swollen leg, sudden chest pain, trouble breathing).
Use in Elderly Patients
Category D
The classification depends on the dosage form. Systemic use (for example estrogen patch, tablet, gel): Avoid use in older adults. In systemic use, consider potential adverse effects, such as risk of cardiovascular diseases and venous thromboembolism. Consider potential interactions. Topical treatment of the vagina: Suitable for older adults. No significant systemic absorption. (updated 21.10.2024)