Estring
Estring vaginal ring is a hormone replacement therapy product used to relieve vaginal dryness and irritation related to menopause.
How to Use
Dosage
The Estring ring releases 7.5 micrograms of estradiol per day. The ring should be replaced with a new one every three months.
Method
Wash your hands thoroughly. Stand with one foot on a chair or lie on your back with your legs bent. Squeeze the ring into an oval shape and insert it as deeply as possible into the vagina, upwards and backwards.
The maximum daily dose is 7.5 micrograms of estradiol, released from the ring.
Possible Side Effects
- •Vaginal discharge
- •Urinary tract infection
- •Upper respiratory tract infection
- •Sinusitis
- •Vaginitis (inflammation of the vagina)
- •Genital yeast infection
- •Insomnia
- •Headache
- •Hot flashes
- •Abdominal pain
- •Lower abdominal pain
- •Uncomfortable feeling in stomach, anus, or rectum
- •Nausea
- •Generalized itching
- •Heavy sweating
- •Joint symptoms (e.g., joint pain, arthritis)
- •Back pain
- •Uncomfortable feeling in bladder area
- •Uncomfortable feeling in external genitalia
- •Vaginal irritation or discomfort
- •Urinary and genital itching
- •Breast symptoms (e.g., swelling, pain)
- •Flu-like symptoms
- •Allergic reactions
- •Vaginal sores or ulcers
- •Ring getting stuck to the vaginal wall
Important Warnings
- Do not use Estring if you are allergic to estradiol or any other ingredients.
- Do not use Estring if you have or have had breast cancer, or any cancer sensitive to estrogen (e.g., uterine lining cancer).
- If you have unexplained vaginal bleeding, do not use Estring.
- Do not use Estring if you have had a blood clot (e.g., in a leg or lung), or if you have a blood clotting disorder or a recent heart attack/stroke.
- Do not use Estring if you have had liver disease and your liver tests have not returned to normal.
Show 2 more warnings
- If you become pregnant while using Estring, stop immediately and contact your doctor.
- Stop using Estring immediately and contact your doctor if you experience severe symptoms like yellow skin, high blood pressure, a new migraine headache, or signs of a blood clot (e.g., leg pain, chest pain, shortness of breath).
Use in Elderly Patients
The classification depends on the dosage form. Systemic use (for example estrogen patch, tablet, gel): Avoid use in older adults. In systemic use, consider potential adverse effects, such as risk of cardiovascular diseases and venous thromboembolism. Consider potential interactions. Topical treatment of the vagina: Suitable for older adults. No significant systemic absorption. (updated 21.10.2024)