Esomeprazol Orion
Esomeprazol Orion is a medicine that reduces stomach acid, used for short-term treatment of reflux symptoms like heartburn and acid regurgitation in adults.
Form
enterotabletti
Strength
20 mg
Active Ingredient
Esomeprazole magnesium
Manufacturer
Sun Pharmaceutical Industries Europe B.V.
How to Use
Dosage
The usual dose is one tablet (20 mg) once a day.
Method
Take the tablet whole with water. You can take it with or without food. Do not chew or crush the tablet as it has a special coating that protects the medicine from stomach acid.
Important
Do not take more than one tablet (20 mg) per day.
Possible Side Effects
COMMON
- •Headache
- •Stomach or gut issues: diarrhea, stomach pain, constipation, gas
- •Feeling sick (nausea) or vomiting
- •Small, harmless growths in the stomach (polyps)
RARE
- •Swelling of the feet and ankles
- •Sleep problems (insomnia), drowsiness
- •Dizziness, tingling or prickling sensation
- •Spinning sensation (vertigo)
- •Dry mouth
- •Changes in liver blood tests
- •Rash, hives, and itchy skin
- •Bone fractures (hip, wrist, or spine) if used for a long time at high doses
- •Changes in blood cell counts (e.g., fewer white blood cells or platelets, leading to weakness, bruising, or infections)
- •Low sodium levels in the blood (can cause weakness, vomiting, cramps)
- •Feeling restless, confused, or depressed
- •Changes in taste
- •Vision problems, such as blurred vision
- •Wheezing or shortness of breath (bronchospasm)
- •Inflammation in the mouth
- •Thrush (a white fungal infection in the mouth, throat, or esophagus)
- •Liver problems, including jaundice (yellow skin/eyes, dark urine, tiredness)
- •Hair loss (alopecia)
- •Rash when exposed to sunlight
- •Joint or muscle pain
- •General feeling of being unwell or lack of energy
- •Increased sweating
- •Low levels of red blood cells, white blood cells, and platelets (pancytopenia)
- •Aggressiveness
- •Hallucinations (seeing, feeling, or hearing things that are not real)
- •Severe liver problems leading to liver failure and brain inflammation
- •Sudden severe rash, blistering, or peeling skin (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis)
- •Muscle weakness
- •Severe kidney problems
- •Enlarged breasts in men
- •Low magnesium levels in the blood (can cause weakness, vomiting, cramps, tremors, and heart rhythm changes). Very low levels can also affect calcium and potassium.
- •Inflammation of the intestine (causing diarrhea)
- •Rash with possible joint pain
Important Warnings
- Do not take this medicine if you are allergic to esomeprazole or any other ingredients in it, or to other similar stomach acid medicines (proton pump inhibitors).
- Do not take this medicine if you are taking nelfinavir, a medicine for HIV infection.
- Do not take this medicine if you have ever had a severe skin rash, skin peeling, blisters, or mouth sores after taking Esomeprazol Orion or similar medicines.
- Contact a doctor immediately if you lose a lot of weight for no clear reason.
- Contact a doctor immediately if you have trouble or pain when swallowing.
Show 5 more warnings
- Contact a doctor immediately if you start to vomit food or blood, especially if it looks like dark coffee grounds.
- Contact a doctor immediately if your stools are dark or bloody.
- Contact a doctor immediately if you have severe or lasting diarrhea, as this medicine may slightly increase the risk of infectious diarrhea.
- Contact a doctor immediately if you get a rash, especially on areas exposed to the sun, as your treatment may need to be stopped.
- Long-term use (over one year) of this medicine may slightly increase the risk of bone fractures (hip, wrist, or spine).
Use in Elderly Patients
Category A
Suitable for older adults. For short-term use only. Consider the numerous potential interactions, especially with clopidogrel and (es)citalopram. Avoid long-term use. Long-term use carries an increased risk of adverse effects. Risk of hypomagnesemia in prolonged use. (updated 10.11.2025)