Esketamine Orifarm
Esketamine Orifarm is a medicine that helps you sleep or reduces pain during surgery; it can be given as an injection into a vein or muscle.
Form
injektio-/infuusioneste, liuos
Strength
5 mg/ml
Active Ingredient
Esketamine hydrochloride
Manufacturer
Orifarm Generics A/S
How to Use
Dosage
Your doctor will decide your dose and how often you get it; only your doctor can change your dose.
Method
A specialist doctor or nurse will give you Esketamine Orifarm as a slow injection into a vein or muscle, and it can also be given as an infusion or repeated if needed.
Important
Your doctor will determine your maximum daily dose; long-term use (more than 3 days) or misuse can cause bladder infections and liver damage.
Possible Side Effects
COMMON
- •Faster heart rate
- •Increased blood pressure
- •Throat spasms
- •Weakened breathing
- •Increased mucus in the lungs
- •Blurred vision
- •Nausea
- •Vomiting
- •Increased salivation
- •Waking reactions after anesthesia, such as vivid dreams, nightmares, dizziness, and restlessness
RARE
- •Double vision
- •Increased eye pressure
- •Involuntary movements resembling convulsions
- •Measles-like rash, skin rash
- •Pain and/or redness at the injection site
- •Irregular or slow heart rate
- •Low blood pressure
- •Sudden rash, breathing problems, and fainting (within minutes to hours) due to hypersensitivity (anaphylactic reaction/shock). This can be fatal.
Important Warnings
- Do not use if you are allergic to esketamine or any other ingredients in this medicine.
- Do not use if you have high blood pressure or increased pressure in your head.
- Do not use if you have eclampsia or pre-eclampsia (a pregnancy complication with high blood pressure).
- Do not use with xanthine derivatives or ergometrine (a medicine used to start labor).
- This medicine should not be given as the only anesthetic if you have calcifications in your heart arteries.
Show 14 more warnings
- Tell your doctor if you have a weak heart (heart failure) or untreated high blood pressure.
- Tell your doctor if you have sudden severe chest pain (angina).
- Tell your doctor if you have increased pressure in your head due to a stroke or illness.
- Tell your doctor if you have diseases of the brain or spinal cord.
- Tell your doctor if you need an eye exam or eye surgery.
- Tell your doctor if you are under the influence of alcohol.
- Tell your doctor if you have or have had severe mental health problems.
- Tell your doctor if you have an overactive thyroid that is not well controlled.
- Tell your doctor if you have situations during childbirth where the uterus muscle needs to be relaxed (e.g., threatened uterine rupture).
- Tell your doctor if you have a history of drug abuse or addiction.
- Tell your doctor if you have impaired liver function.
- Tell your doctor if you are going to have blood or urine tests, as Esketamine Orifarm can affect the results.
- Tell your doctor if you experience shortness of breath after the injection.
- Do not drive or operate machinery for at least 24 hours after treatment, and do not drink alcohol for 24 hours after treatment.