Erlotinib Krka
Erlotinib Krka is a medicine for cancer that works by blocking a protein called EGFR, which helps cancer cells grow and spread.
Form
tabletti, kalvopäällysteinen
Strength
25 mg
Active Ingredient
Erlotinib hydrochloride
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
For non-small cell lung cancer, the usual dose is one 150 mg tablet daily. For pancreatic cancer that has spread, the usual dose is one 100 mg tablet daily, taken with gemcitabine.
Method
Take the tablet at least one hour before or two hours after a meal.
Important
The maximum daily dose is usually 150 mg or 100 mg, depending on your condition, as prescribed by your doctor. Your doctor may adjust your dose.
Possible Side Effects
COMMON
- •Diarrhea and vomiting
- •Eye irritation (e.g., inflammation of the cornea or conjunctiva)
- •Rash (may worsen with sun exposure)
- •Infection
- •Loss of appetite, weight loss
- •Depression
- •Headache, changes in skin sensation or numbness in limbs
- •Shortness of breath, cough
- •Nausea
- •Mouth irritation
- •Stomach pain, indigestion, flatulence
- •Abnormal liver function test results
- •Itching
- •Fatigue, fever, chills
- •Dry skin
- •Hair loss
- •Nosebleeds
- •Stomach or intestinal bleeding
- •Inflammation around fingernails
- •Hair follicle inflammation
- •Acne
- •Cracked skin
- •Impaired kidney function (when Erlotinib Krka is used with chemotherapy for unapproved indications)
RARE
- •Interstitial lung disease (a serious lung condition)
- •Gastrointestinal perforation (a hole in the stomach or intestine)
- •Liver inflammation (hepatitis), sometimes leading to liver failure
- •Kidney inflammation (nephritis)
- •Excess protein in urine (proteinuria)
- •Eyelash changes
- •Increased body and facial hair in men
- •Skin hyperpigmentation (darkening of skin)
- •Eyebrow changes
- •Brittle and loose nails
- •Red or painful palms or soles (hand-foot syndrome)
- •Corneal ulcers or perforations (sores or holes in the eye's surface)
- •Severe blistering or peeling skin rash (e.g., Stevens-Johnson syndrome)
- •Inflammation of the iris (colored part of the eye)
Important Warnings
- Do not take Erlotinib Krka if you are allergic to erlotinib or any other ingredients in this medicine.
- Tell your doctor immediately if you suddenly have trouble breathing, with coughing or fever.
- Contact your doctor immediately if you have severe or ongoing diarrhea, nausea, loss of appetite, or vomiting, as you may need hospital care.
- Inform your doctor if you have had liver problems, as this medicine can cause severe liver issues, even leading to death. Your doctor will monitor your liver function.
- Tell your doctor if you have severe stomach pain, burning, peeling skin rashes, sudden or worsening eye redness or pain, increased tearing, blurred vision, or light sensitivity.
Show 2 more warnings
- Avoid becoming pregnant during treatment and for at least 2 weeks after the last tablet. Do not breastfeed during treatment and for at least 2 weeks after the last tablet.
- Do not take Erlotinib Krka with food.