Eribulin medac
Eribulin medac is a cancer medicine that works by stopping cancer cells from growing and spreading.
Form
injektioneste, liuos
Strength
0.44 mg/ml
Active Ingredient
Eribulin mesylate
Manufacturer
Medac Gesellschaft Für Klinische Spezialpräparate mbH
How to Use
Dosage
The usual dose of Eribulin medac is 1.23 mg/m², but your doctor may change this based on blood test results or other factors.
Method
A trained healthcare professional will give Eribulin medac as an injection into a vein, which takes 2-5 minutes. A saline flush is recommended afterwards.
Important
Eribulin medac is usually given on day 1 and day 8 of each 21-day treatment cycle. Your doctor will decide how many cycles you need and may adjust or delay your dose based on blood tests.
Possible Side Effects
COMMON
- •Decreased white or red blood cell count
- •Tiredness or weakness
- •Nausea, vomiting, constipation, diarrhea
- •Numbness, tingling or prickling sensation
- •Fever
- •Loss of appetite, weight loss
- •Difficulty breathing, cough
- •Joint, muscle, and back pain
- •Headache
- •Hair loss
- •Decreased platelet count (may cause bruising or prolonged bleeding time)
- •Febrile infection, pneumonia, chills
- •Fast heartbeat, skin redness
- •Dizziness, lightheadedness
- •Increased tear production, conjunctivitis (redness and soreness of the eye surface), nosebleed
- •Dehydration, dry mouth, cold sores, oral thrush, indigestion, heartburn, stomach pain or bloating
- •Soft tissue swelling, pain (especially chest pain, back pain, and bone pain), muscle cramps or muscle weakness
- •Mouth, respiratory tract, and urinary tract infections, pain when urinating
- •Sore throat, sore or runny nose, flu-like symptoms, sore throat
- •Abnormal liver function test results, changes in blood sugar, bilirubin, phosphate, potassium, magnesium, or calcium levels
- •Difficulty sleeping, depression, altered taste
- •Rash, itching, nail problems, dry or red skin
- •Excessive sweating (including night sweats)
- •Ringing in the ears
- •Blood clots in the lungs
- •Shingles
- •Skin swelling and numbness in hands and feet
RARE
- •Blood clots
- •Abnormal liver function tests (liver toxicity)
- •Kidney failure, blood or protein in urine
- •Widespread lung inflammation that may lead to scarring
- •Pancreatitis
- •Mouth sores
- •Severe blood clotting disorder leading to widespread blood clot formation and internal bleeding
Important Warnings
- Do not use if you are allergic to eribulin or any other ingredient in this medicine.
- Do not use if you are breastfeeding.
- This medicine is not for children aged 0-18 years.
- Women who can get pregnant must use effective contraception during treatment and for at least 7 months after the last dose. Eribulin medac can cause serious birth defects.
- Men must use effective contraception during treatment and for at least 4 months after the last dose, and should not father a child. Eribulin medac can cause permanent fertility problems in men.
Show 8 more warnings
- Tell your doctor if you have liver problems.
- Tell your doctor if you have a fever or an infection.
- Tell your doctor if you experience numbness, tingling, prickling sensations, touch sensitivity, or muscle weakness.
- Tell your doctor if you have heart problems.
- Do not drive or operate machinery if you feel tired or dizzy.
- Seek immediate medical attention if you have fever with a fast heartbeat, fast breathing, cold/pale/clammy/blotchy skin, and/or confusion, as these could be signs of sepsis (blood poisoning).
- Seek immediate medical attention if you have difficulty breathing or swelling of your face, mouth, tongue, or throat, as these could be signs of a serious allergic reaction.
- Seek immediate medical attention if you develop severe blistering skin rashes on your skin, in your mouth, eyes, or genitals, as these could be signs of Stevens-Johnson syndrome/toxic epidermal necrolysis, which can be life-threatening.