Eltrombopag Avansor
Eltrombopag Avansor helps increase the number of platelets in your blood, which are cells that help prevent or stop bleeding.
Form
tabletti, kalvopäällysteinen
Strength
25 mg
Active Ingredient
Eltrombopag olamine
Manufacturer
Avansor Pharma Oy
How to Use
Dosage
For ITP: Adults and children (6-17 years old) usually start with one 50 mg tablet once daily. If you are of East or Southeast Asian origin, you might start with 25 mg. Children (1-5 years old) usually start with one 25 mg tablet once daily. For Hepatitis C: Adults usually start with one 25 mg tablet once daily. If you are of East or Southeast Asian origin, you will start with the same 25 mg dose.
Method
Swallow the tablet whole with some water.
Important
Do not take more than one dose of Eltrombopag Avansor per day.
Possible Side Effects
COMMON
- •Upper respiratory infection (e.g., common cold, sinus infection, sore throat)
- •Cough
- •Nausea and diarrhea
- •Back pain
- •Increased liver enzymes (seen in blood tests)
- •Stomach pain
- •Fever
- •Loss of appetite
- •Headache
- •Itching
- •Swollen hands or feet
- •Unusual hair loss
- •Muscle pain or weakness
- •Feeling tired or weak, flu-like symptoms
- •Anemia (low red blood cells, seen in blood tests)
RARE
- •Flu, cold sores, pneumonia, lung inflammation
- •Sinus irritation and inflammation (swelling)
- •Tonsil inflammation (swelling) and infection
- •Nose and throat inflammation
- •Gum inflammation
- •Sore throat and discomfort swallowing
- •Trouble sleeping (insomnia)
- •Feeling down (depression)
- •Reduced skin sensitivity (tingling, numbness)
- •Drowsiness
- •Migraine
- •Eye problems (e.g., dry eyes, eye pain, blurry or reduced vision, abnormal eye tests, increased tearing, cloudy lens (cataract), retinal bleeding, yellowing of whites of eyes, small yellow deposits on retina)
- •Ear pain
- •Spinning sensation (vertigo)
- •Pain, swelling, warmth, redness, or tenderness in one leg (signs of deep vein thrombosis)
- •Bleeding under the skin (hematoma)
- •Hot flashes
- •Dry mouth, sore mouth or tongue, bleeding gums, mouth sores, toothache
- •Gas (flatulence)
- •Heavy sweating
- •Itchy rash with bumps (urticaria)
- •Red spots on skin
- •Changes in skin appearance
- •Muscle cramps
- •Bone pain
- •Foamy urine (signs of protein)
- •Heavy menstrual bleeding
- •Feeling of warmth
- •Chest pain
- •Low platelet count (thrombocytopenia, seen in blood tests)
- •Low white blood cell count (seen in blood tests)
- •Low hemoglobin levels (seen in blood tests)
- •Increased eosinophils (seen in blood tests)
- •High white blood cell count (leukocytosis, seen in blood tests)
- •High uric acid levels (seen in blood tests)
- •Low potassium levels (seen in blood tests)
- •High liver enzymes (AST, seen in blood tests)
- •High bilirubin levels (seen in blood tests)
- •Increased levels of some proteins (seen in blood tests)
- •High creatinine levels (seen in blood tests)
- •High alkaline phosphatase levels (seen in blood tests)
- •Skin infection
- •Rectal or colon cancer
- •Allergic reaction
- •Joint pain and swelling from uric acid (gout)
- •Lack of interest
- •Mood changes
- •Uncontrollable crying or crying at unexpected times
- •Balance, speech, and nerve problems
- •Tremors
- •Paralysis on one side of the body
- •Migraine with aura
- •Nerve damage
- •Blood vessel widening or swelling (causing headache)
- •Increased tearing
- •Cloudy lens (cataract)
- •Retinal bleeding
- •Fast heartbeat
- •Irregular heartbeat
- •Bluish skin color
- •Heart rhythm problems (prolonged QT interval)
- •Reduced blood flow to part of the heart
- •Pain, swelling, or redness around a vein (signs of a blood clot)
- •Blood clot
- •Facial and neck redness
- •Sudden shortness of breath, sharp chest pain, and/or fast breathing (sign of lung blood clot)
- •Part of the lung not working due to blocked lung artery
- •Nose, throat, and sinus symptoms (sleep breathing problems)
- •Mouth discomfort
- •Blisters/sores in mouth and throat
- •Digestive symptoms (frequent bowel movements, food poisoning, blood in stool, vomiting blood, rectal bleeding, changes in stool color, abdominal swelling, constipation)
- •Yellow skin and/or abdominal pain (signs of bile duct blockage, liver changes or inflammation)
- •Drug-induced liver damage
- •Painful or abnormal skin sensations
- •Skin discoloration
- •Peeling skin (exfoliation)
- •Redness
- •Cold sweats
- •Kidney problems (kidney inflammation, frequent nighttime urination, kidney failure, white blood cells in urine)
- •Anxiety
- •Skin bleeding around a catheter
- •Redness or swelling around a wound
- •General feeling of illness (malaise)
- •Feeling of a foreign body
- •Sunburn
- •Changes in red blood cell shape (seen in blood tests)
- •Anemia (due to too much red blood cell destruction, seen in blood tests)
- •Increased myelocytes (seen in blood tests)
- •Increased band neutrophils (seen in blood tests)
- •Presence of early white blood cells (may indicate certain diseases, seen in blood tests)
- •Increased platelet count (seen in blood tests)
- •Increased hemoglobin levels (seen in blood tests)
- •Low calcium levels (seen in blood tests)
- •High blood urea levels (seen in blood tests)
- •High protein in urine (seen in blood tests)
- •Itchy nose
- •Runny or blocked nose
- •Sneezing
- •Nose and throat pain
- •Urinary tract infection
- •Bronchial lining inflammation
- •Nasal passages, throat, and mouth inflammation
- •Cold-like symptoms
- •Inflamed or sore mouth
- •Weight loss
- •Abnormal drowsiness
- •Reduced brain function (due to liver damage)
- •Tingling or numbness in hands or feet
- •Yellowing of whites of eyes
- •Cough with mucus
- •Enlarged veins and bleeding in the esophagus
- •Liver tumor
- •Eczema
- •Unusual skin growths
- •Limb pain (arms, legs, hands, or feet)
- •Skin reaction (redness, swelling, and pain at injection site)
- •Fluid retention in body or limbs (swelling)
- •Nervousness
- •Confusion
- •Agitation
- •Stomach inflammation
- •Blood clots in liver veins (liver damage), liver failure
- •Night sweats
- •Painful urination
- •Abnormal blood clot formation in small blood vessels and kidney failure
- •Bruising at injection site
- •High blood sugar levels (seen in blood tests)
- •Low neutrophil count (seen in blood tests)
- •Low blood albumin levels (seen in blood tests)
- •Changes in blood clotting enzymes (seen in blood tests)
- •High blood albumin levels (seen in blood tests)
- •High total protein levels (seen in blood tests)
- •Increased urine pH (seen in blood tests)
Important Warnings
- Do not take this medicine if you are allergic to eltrombopag or any other ingredient in this medicine.
- Tell your doctor if you have liver problems, as there's a higher risk of serious liver damage and blood clots, especially with chronic liver disease.
- Talk to your doctor if you have a risk of blood clots or if they run in your family.
- Do not take this medicine with dairy products, antacids, or mineral supplements (like iron, calcium, magnesium, aluminum, selenium, and zinc) for 4 hours before and 2 hours after your dose, as they can stop the medicine from working properly.
- Do not stop taking Eltrombopag Avansor without talking to your doctor, as your platelet count will likely drop again within days.
Show 2 more warnings
- Do not use this medicine if you are pregnant or breastfeeding unless your doctor specifically advises it.
- This medicine can cause dizziness or other side effects that affect your concentration, so do not drive or use machines unless you are sure you are not affected.