Eldepryl

Eldepryl is a medicine used to treat Parkinson's disease, either alone or with other medications.

Form
tabletti
Strength
5 mg
Active Ingredient
Selegiline hydrochloride
Manufacturer
Orion Corporation

How to Use

Dosage

The starting dose is 5 mg in the morning. The dose can be increased to 10 mg per day.

Method

Take this medicine exactly as your doctor has told you. The dose can be taken in the morning or divided into two doses. The 10 mg tablet can be divided.

Important

The maximum daily dose is 10 mg.

Possible Side Effects

COMMON
  • confusion, hallucinations
  • involuntary movements, dizziness, headache
  • slow heart rate
  • nausea
  • changes in liver values
RARE
  • agitation
  • heart rhythm disorders
  • drop in blood pressure when standing up
  • rash
  • difficulty urinating
  • mood changes
  • mild, temporary sleep disturbances (e.g., insomnia)
  • fast heart rate
  • dry mouth
  • impulse control disorders and compulsive behaviors
  • urinary retention

Important Warnings

  • Do not take if you are allergic to selegiline or any other ingredients in the medicine.
  • Do not take if you are using certain antidepressants (like SSRIs, SNRIs, tricyclic antidepressants), pain relievers (like pethidine, tramadol), or other MAO inhibitors.
  • Do not take if you have an active stomach or duodenal ulcer.
  • Tell your doctor if you have high blood pressure, heart problems, mental health issues, or liver or kidney problems.
  • Tell your doctor if you are taking levodopa or if you are going to have surgery under general anesthesia.
Show 3 more warnings
  • Avoid alcohol while taking Eldepryl.
  • If you are pregnant, breastfeeding, or planning to get pregnant, ask your doctor for advice.
  • This medicine may affect your ability to drive or use machines.

Use in Elderly Patients

Category D

Avoid use in older adults. Serotonergic. Reduce the dose already in mild renal impairment. Adverse effects include orthostatic hypotension, hallucinations, confusion, dyskinesia, headache, dizziness and bradycardia. Do not use together with other serotonergic preparations. (updated 6.10.2025)