Edoxaban Krka

This medicine helps prevent blood clots by blocking a substance in your blood called factor Xa.

Form
tabletti, kalvopäällysteinen
Strength
60 mg
Active Ingredient
Edoxaban tosylate monohydrate
Manufacturer
KRKA d.d. Novo mesto

How to Use

Dosage

Usually, take one 60 mg tablet once daily. Your doctor may prescribe one 30 mg tablet once daily if you have kidney problems, weigh 60 kg or less, or are taking certain other medicines.

Method

Swallow the tablet whole with water. You can take it with or without food. If you have trouble swallowing the tablet whole, you can crush it and mix with water or applesauce; discuss this with your doctor first.

Important

The maximum daily dose is one 60 mg tablet, unless your doctor has prescribed a lower dose (30 mg) due to certain conditions or your body weight.

Possible Side Effects

COMMON
  • Stomach ache
  • Abnormal liver test results (shown in blood tests)
  • Bleeding from or under the skin
  • Anemia (low red blood cell count)
  • Nosebleed
  • Vaginal bleeding
  • Rash
  • Intestinal bleeding
  • Bleeding from the mouth and/or throat
  • Blood in urine
  • Bleeding after a puncture wound
  • Stomach bleeding
  • Dizziness
  • Nausea
  • Headache
  • Itching
RARE
  • Eye bleeding
  • Bleeding from a surgical wound after an operation
  • Coughing up blood (bloody sputum)
  • Brain bleeding
  • Other types of bleeding
  • Low platelet count (which can affect blood clotting)
  • Allergic reaction
  • Hives
  • Muscle bleeding
  • Joint bleeding
  • Abdominal bleeding
  • Heart bleeding
  • Bleeding inside the skull
  • Bleeding after a surgical procedure
  • Allergic shock (severe allergic reaction)
  • Swelling in any part of the body due to an allergic reaction
  • Kidney bleeding, sometimes with blood in urine, causing kidney problems

Important Warnings

  • Do not take this medicine if you are allergic to edoxaban or any other ingredients in it.
  • Do not take this medicine if you are currently bleeding.
  • Do not take this medicine if you have a condition that increases your risk of severe bleeding, such as a stomach ulcer or recent brain or eye surgery.
  • Do not use this medicine at the same time as other blood thinners, unless your doctor has told you to switch treatments or if heparin is used to keep a tube open.
  • Do not take this medicine if you have a severe liver disease that increases your risk of bleeding.
Show 6 more warnings
  • Do not take this medicine if you have uncontrolled high blood pressure.
  • Do not take this medicine if you are pregnant or breastfeeding.
  • Talk to your doctor if you have an increased risk of bleeding due to conditions like severe kidney disease, liver disease, a bleeding disorder, or recent bleeding in the brain.
  • Talk to your doctor if you have a mechanical heart valve.
  • Talk to your doctor if you know you have antiphospholipid syndrome.
  • Tell your doctor if you are going to have surgery; you may need to stop taking this medicine at least 24 hours before.