Ebetrex

Ebetrex is a medicine that slows down the growth of fast-growing cells, reduces unwanted immune reactions, and lessens inflammation, used to treat severe rheumatoid arthritis, juvenile idiopathic arthritis, and psoriasis.

Form
injektioneste, liuos, esitäytetty ruisku
Strength
20 mg/ml
Active Ingredient
Methotrexate
Manufacturer
Ebewe Pharma Ges.m.b.H. Nfg.KG

How to Use

Dosage

The typical starting dose is 7.5 mg once a week, often increased to 15-20 mg weekly depending on your condition.

Method

This medicine is given as an injection under the skin, into a muscle, or into a vein. For children and adolescents, it should not be given into a vein.

Important

Do not exceed 25 mg (for rheumatoid arthritis) or 30 mg (for psoriasis) in a single weekly dose. This medicine is taken only once a week.

Possible Side Effects

COMMON
  • Loss of appetite, feeling sick (nausea), throwing up (vomiting), stomach pain, mouth sores, diarrhea.
  • Headache, tiredness, skin rash or itching.
  • Increased liver enzymes (seen in blood tests), changes in blood cells which can make you feel very tired.
RARE
  • Severe allergic reaction with sudden wheezing, trouble breathing, swelling of your face/lips/eyelids, or a widespread rash and dizziness.
  • Severe skin reactions like painful blisters or skin peeling.
  • Serious infections, a severe drop in blood cells (leading to easy bruising, bleeding, or constant infections), or blood clots.
  • Lung problems (like cough, shortness of breath, chest pain, fever), liver damage (yellow skin/eyes), or kidney failure (little to no urine).
  • New or worsening problems with muscle weakness, vision, thinking, memory, confusion, or seizures.
  • Miscarriage, birth defects, or problems with egg/sperm formation.

Important Warnings

  • This medicine is taken only ONCE A WEEK. Taking it more often or in too high a dose can cause very serious or even deadly side effects.
  • Do not use if you are allergic to methotrexate or any other ingredient in Ebetrex.
  • Do not use if you have severe kidney or liver disease.
  • Do not use if you are pregnant, planning to become pregnant, or breastfeeding.
  • Avoid using if you have a severe or active infection, a weakened immune system, or serious blood disorders.
Show 3 more warnings
  • Do not drink alcohol while taking this medicine.
  • This medicine can make your skin more sensitive to sunlight. Avoid strong sun exposure and tanning beds.
  • If you notice new or worsening problems with muscle weakness, vision, thinking, memory, or personality changes, contact your doctor immediately. These could be signs of a very rare but serious brain infection.