Duloxetin Stada
Duloxetin Stada is a medicine that contains duloxetine and helps by increasing serotonin and noradrenaline levels in the brain to treat depression, anxiety, and nerve pain.
Form
enterokapseli, kova
Strength
60 mg
Active Ingredient
Duloxetine hydrochloride
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
For depression and diabetic nerve pain, the usual dose is 60 mg once daily. For generalized anxiety disorder, treatment starts with 30 mg once daily, usually increasing to 60 mg, but your doctor can adjust it up to 120 mg daily.
Method
Take the capsule whole with water, by mouth. Try to take it at the same time each day to help you remember.
Important
Do not take more than the daily dose prescribed by your doctor, which can be up to 120 mg.
Possible Side Effects
COMMON
- •Headache
- •Drowsiness
- •Nausea
- •Dry mouth
- •Loss of appetite
- •Difficulty sleeping
- •Agitation
- •Decreased sex drive
- •Anxiety
- •Problems reaching orgasm
- •Unusual dreams
- •Dizziness
- •Lethargy
- •Tremor
- •Numbness, tingling or prickling sensations (paresthesia)
- •Blurred vision
- •Ringing in the ears (tinnitus)
- •Palpitations
- •High blood pressure
- •Flushing
- •Increased yawning
- •Constipation
- •Diarrhea
- •Stomach pain
- •Vomiting
- •Heartburn or indigestion
- •Gas
- •Increased sweating
- •Itchy rash
- •Muscle pain
- •Muscle spasm
- •Painful urination
- •Increased urination
- •Erectile dysfunction
- •Ejaculation problems
- •Falls (mostly in older people)
- •Fatigue
- •Weight loss
RARE
- •Sore throat leading to hoarseness
- •Suicidal thoughts
- •Sleep problems
- •Teeth grinding
- •Clenching teeth
- •Feeling disoriented (e.g., about time or place)
- •Lack of initiative
- •Seizures
- •Involuntary muscle movements
- •Restlessness or inability to sit or stand still
- •Nervousness
- •Difficulty concentrating
- •Changes in taste
- •Difficulty controlling muscle movements (e.g., poor muscle coordination or uncontrolled muscle movements)
- •Restless legs syndrome
- •Poor quality sleep
- •Enlarged pupils (black part of the eye)
- •Vision problems
- •Dizziness or spinning sensation (vertigo)
- •Ear pain
- •Fast and/or irregular heartbeat
- •Fainting
- •Dizziness, weakness or lightheadedness upon standing up
- •Cold fingers and/or toes
- •Throat tightness
- •Nosebleeds
- •Vomiting blood or black tarry stools
- •Bowel inflammation
- •Burping
- •Difficulty swallowing
- •Liver inflammation, which can cause stomach pain and yellowing of the skin or whites of the eyes (jaundice)
- •Night sweats
- •Hives
- •Cold sweats
- •Sensitivity to sunlight
- •Increased bruising
- •Muscle stiffness
- •Muscle twitching
- •Difficulty urinating or inability to urinate
- •Difficulty starting urination
- •Needing to urinate at night
- •Needing to urinate more often than usual
- •Weak urine stream
- •Abnormal vaginal bleeding
- •Menstrual problems such as heavy, painful, irregular, or prolonged periods
- •Unusually light or absent periods
- •Pain in the testicles or scrotum
- •Chest pain
- •Feeling cold
- •Thirst
- •Muscle tremors
- •Feeling hot
- •Abnormal walking
- •Weight gain
- •Severe allergic reaction with breathing difficulties, dizziness, swelling of the tongue or lips, other allergic reactions
- •Underactive thyroid gland, which can cause fatigue or weight gain
- •Dehydration, low sodium levels in the blood (in elderly, symptoms can include dizziness, weakness, confusion, drowsiness, and deep fatigue, or nausea and malaise. Severe symptoms include fainting, twitching, and falls), Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
- •Suicidal behavior
- •Mania (overactivity, restless thoughts and decreased need for sleep)
- •Hallucinations
- •Aggressive behavior and anger
- •Serotonin syndrome (a rare condition that can cause extreme happiness, drowsiness, clumsiness, restlessness, feeling intoxicated, fever, sweating, and stiff muscles)
- •Seizures
- •Increased eye pressure (glaucoma)
- •Cough
- •Wheezing and shortness of breath, possibly with high fever
- •Mouth inflammation
- •Bright red blood in stools
- •Bad breath
- •Colon inflammation (leading to diarrhea)
- •Liver failure, yellowing of the skin or whites of the eyes (jaundice)
- •Stevens-Johnson syndrome (a severe illness with blisters on the skin, mouth, eyes, and genitals)
- •Severe allergic reaction causing swelling of the face and throat (angioedema)
- •Jaw muscle spasm leading to lockjaw
- •Unusual urine smell
- •Menopausal symptoms
- •Abnormal milk production in men and women
- •Excessive vaginal bleeding shortly after childbirth (postpartum hemorrhage)
- •Inflammation of blood vessels in the skin (cutaneous vasculitis)
- •Signs and symptoms of a condition called 'stress cardiomyopathy', which may include chest pain, shortness of breath, dizziness, fainting, irregular heartbeat
Important Warnings
- Do not take if you are allergic to duloxetine or any other ingredient in this medicine.
- Do not take if you have liver disease.
- Do not take if you have severe kidney disease.
- Do not take if you are taking or have taken another MAO inhibitor antidepressant in the last 14 days.
- Do not take if you are taking fluvoxamine (for depression), ciprofloxacin, or enoxacin (for infections).
Show 18 more warnings
- Do not take if you are taking another medicine that contains duloxetine.
- Tell your doctor if you have high blood pressure or heart problems.
- Tell your doctor if you are taking other medicines for depression.
- Tell your doctor if you are taking St. John's wort (a herbal remedy).
- Tell your doctor if you have had fits or seizures.
- Tell your doctor if you have had mania (a state of high excitement).
- Tell your doctor if you have bipolar disorder.
- Tell your doctor if you have eye problems like glaucoma (high pressure in the eye).
- Tell your doctor if you have a history of bleeding disorders (tendency to bruise easily), especially if you are pregnant.
- Tell your doctor if you are at risk of low sodium levels in your body (e.g., if you take water pills, especially if you are elderly).
- Tell your doctor if you are currently being treated with another medicine that can cause liver damage.
- This medicine may make you feel restless and unable to sit or stand still. If this happens, tell your doctor.
- Contact your doctor if you experience restlessness, hallucinations, loss of coordination, fast heartbeat, high body temperature, rapid blood pressure changes, overactive reflexes, diarrhea, coma, nausea, or vomiting, as these could be signs of serotonin syndrome.
- If you are depressed or anxious, you may sometimes have thoughts of harming yourself or suicide. If you have such thoughts, contact your doctor immediately or go to a hospital.
- Blood thinning medicines (anticoagulants or antiplatelet agents) can increase the risk of bleeding.
- Be careful if you drink alcohol while taking this medicine.
- This medicine can cause drowsiness and dizziness, so do not drive or use machines until you know how it affects you.
- If you have a sugar intolerance, talk to your doctor before taking this medicine.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Serotonergic. Consider risk of urinary retention. Increases risk of falls. Consider potential interactions. (updated 12.2.2024)