Docetaxel Ebewe
Docetaxel Ebewe is a cancer medicine used to treat various types of cancer, including breast cancer, lung cancer, prostate cancer, stomach cancer, and head and neck cancer.
Form
infuusiokonsentraatti, liuosta varten
Strength
10 mg/ml
Active Ingredient
Docetaxel
Manufacturer
Ebewe Pharma Ges.m.b.H. Nfg.KG
How to Use
Dosage
Your doctor will determine your dose based on your weight, general health, and body surface area.
Method
The medicine is given as an infusion into a vein (drip) in a hospital and takes about one hour.
Important
You usually receive an infusion once every three weeks.
Possible Side Effects
COMMON
- •Infections, reduced red or white blood cells, or platelets
- •Fever
- •Allergic reactions (facial flushing, skin rash, itching, chest tightness, breathing difficulties, chills, back pain, low blood pressure)
- •Loss of appetite
- •Insomnia (difficulty sleeping)
- •Numbness, tingling, or joint or muscle pain
- •Headache
- •Changes in taste
- •Eye inflammation or increased tear production
- •Swelling due to fluid buildup (lymphatic dysfunction)
- •Shortness of breath
- •Runny nose, inflamed throat and nose, cough
- •Nosebleed
- •Mouth sores
- •Stomach problems (nausea, vomiting, diarrhea, and constipation)
- •Stomach pain
- •Digestive problems
- •Hair loss (usually temporary)
- •Redness and swelling of palms and soles, skin peeling
- •Nail changes or loss
- •Muscle aches, back or bone pain
- •Menstrual cycle changes or absence
- •Swelling of hands, feet, or legs
- •Fatigue or flu-like symptoms
- •Weight gain or loss
- •Upper respiratory infection
- •Oral thrush (yeast infection in the mouth)
- •Dehydration
- •Dizziness
- •Hearing loss
- •Low blood pressure, irregular or fast heartbeat
- •Heart failure
- •Esophagitis (inflammation of the esophagus)
- •Dry mouth
- •Difficulty or pain when swallowing
- •Bleeding
- •Increased liver enzyme values (requires regular blood tests)
- •Increased blood sugar levels (diabetes)
- •Decreased blood potassium, calcium, and/or phosphate levels
RARE
- •Fainting
- •Injection site reactions, skin reactions, vein inflammation or swelling
- •Blood clots
- •Acute myeloid leukemia and myelodysplastic syndrome (types of blood cancer)
- •Colon or small intestine inflammation, which can be fatal; bowel perforation
- •Interstitial lung disease (lung inflammation causing cough and shortness of breath)
- •Pneumonia (lung infection)
- •Lung fibrosis (scarring and thickening of lung tissue causing shortness of breath)
- •Blurred vision due to retinal swelling (cystoid macular edema)
- •Decreased blood sodium, potassium, magnesium, and/or calcium levels (electrolyte imbalance)
- •Ventricular arrhythmia or tachycardia (irregular/fast heartbeat, severe shortness of breath, dizziness, or fainting)
- •Injection site reactions at previous reaction sites
- •Non-Hodgkin's lymphoma and other cancers (immune system affecting cancer)
- •Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) (blistering, peeling, bleeding, rash, flu-like symptoms)
- •Acute Generalized Exanthematous Pustulosis (AGEP) (red, peeling, widespread rash with pustules, swollen skin, blisters, fever)
- •Tumor lysis syndrome (changes in blood values, seizures, kidney failure, heart rhythm disorders)
- •Myositis (muscle inflammation – muscle pain and weakness, warmth, redness, and swelling)
Important Warnings
- Do not use Docetaxel Ebewe if you are allergic to docetaxel or any other ingredient in this medicine, have too few white blood cells, or severe liver disease.
- Blood tests will be taken before each treatment to ensure your blood cell count and liver function are good.
- Tell your doctor immediately if you have stomach pain, diarrhea, bleeding from the rectum, blood in your stool, or fever, as these can be signs of severe bowel damage.
- Report any vision problems, such as blurred vision, to your doctor so your eyes can be checked immediately.
- Tell your doctor if you have had an allergic reaction to paclitaxel treatment in the past or if you have heart problems.
Show 5 more warnings
- Report immediately if you develop sudden or worsening lung problems, such as fever, shortness of breath, or cough.
- If you experience severe skin reactions such as blistering, peeling, bleeding, or a widespread rash, contact your doctor immediately.
- Docetaxel Ebewe contains alcohol, so discuss with your doctor if you have alcohol dependence, epilepsy, or impaired liver function.
- Do not become pregnant during treatment or for 2 months after treatment. Use effective contraception. Men should not father a child during treatment or for 4 months after treatment and should consider sperm preservation.
- Do not drive or operate machinery if this medicine affects your ability to do so, for example, if you experience side effects.