Dobutamin Hameln
Dobutamin Hameln helps your heart pump blood better, increasing blood flow in your body and widening blood vessels.
Form
infuusiokonsentraatti, liuosta varten
Strength
12.5 mg/ml
Active Ingredient
Dobutamine hydrochloride
Manufacturer
Hameln Pharma GmbH
How to Use
Dosage
The typical dose for adults is 2.5 to 10 micrograms per kilogram of body weight per minute.
Method
Dobutamin Hameln is given as an infusion into a vein by trained healthcare professionals, usually in a hospital, with emergency equipment ready.
Important
The maximum dose given has been up to 40 micrograms per kilogram of body weight per minute.
Possible Side Effects
COMMON
- •Increased heart rate
- •Chest pain
- •Heart rhythm problems
- •Abnormal heart function test (e.g., changes in ECG during stress test)
- •Blood pressure increase or decrease
- •Narrowing of blood vessels
- •Irregular heartbeat or feeling your heart pound
- •Fast heart rate (ventricular tachycardia)
- •Headache
- •Asthma-like symptoms (bronchospasm) or shortness of breath
- •Increase in a type of white blood cells (eosinophilia)
- •Reduced ability of blood to clot
- •Increased need to urinate (with high doses)
- •Nausea (feeling sick)
- •Skin rash
- •Fever
- •Inflammation of the vein at the injection site
- •Allergic reactions (e.g., rash)
- •Inflammation of the heart muscle (eosinophilic myocarditis)
RARE
- •Uncontrolled contractions in the heart chambers (ventricular fibrillation)
- •Heart attack
- •Uncontrolled contractions in the upper heart chambers (atrial fibrillation)
- •Blockage of blood flow from the left ventricle (during dobutamine stress test)
- •Severe allergic reactions (anaphylaxis) or life-threatening asthma attacks
- •Slow heart rate
- •Reduced blood flow to the heart (myocardial ischemia)
- •Low potassium in blood
- •Pinpoint spots on the skin (petechial bleeding)
- •Heart block
- •Narrowing of blood vessels supplying the heart
- •Black areas of dead skin (skin necrosis)
- •Muscle cramps (myoclonus) in patients with severe kidney problems receiving dobutamine
- •Fatal heart rupture (during dobutamine stress test)
- •Restlessness
- •Tingling or numbness (paresthesia)
- •Involuntary muscle movements (tremor)
- •Feeling hot and anxious
- •Muscle spasms
Important Warnings
- Do not take if you are allergic to dobutamine or any other ingredients in this medicine.
- Do not take if you have a narrowing in your heart or blood vessels that prevents blood from filling or pumping properly.
- Do not take if your blood volume is too low.
- Do not take if you have high blood pressure caused by a tumor near your kidney (pheochromocytoma).
- Do not use to check for poor blood flow to your heart if you have certain heart or blood vessel conditions.