Dimethyl fumarate Pharmathen
Dimethyl fumarate Pharmathen is a medicine that treats a type of MS (multiple sclerosis) and helps protect your brain and spinal cord.
Form
enterokapseli, kova
Strength
240 mg
Active Ingredient
Dimethyl fumarate
Manufacturer
Pharmathen S.A.
How to Use
Dosage
The starting dose is 120 mg twice a day for seven days. After that, the usual dose is 240 mg twice a day.
Method
Swallow the capsules whole with water. Do not divide, crush, dissolve, suck, or chew the capsule.
Important
The maximum daily dose is 480 mg.
Possible Side Effects
COMMON
- •Redness on face or body, feeling warm, burning, or itching.
- •Diarrhea.
- •Nausea.
- •Stomach pain or cramps.
- •Stomach or gut inflammation.
- •Vomiting.
- •Upset stomach.
- •Inflammation of the stomach lining.
- •Stomach or bowel issues.
- •Burning feeling.
- •Hot flashes, feeling hot.
- •Itchy skin.
- •Rash.
- •Red or pink spots on skin.
- •Hair loss.
- •Low white blood cell count.
- •Protein in urine.
- •High liver enzymes in blood.
RARE
- •Allergic reactions.
- •Low platelet count.
- •Liver inflammation and high liver enzymes (with bilirubin).
- •Shingles (symptoms include blisters, burning, itching, pain, fever, and weakness).
- •Severe runny nose.
Important Warnings
- Do not take this medicine if you are allergic to dimethyl fumarate or any other ingredient.
- Do not use if you have or are suspected to have a rare brain infection (PML).
- This medicine can affect your white blood cells, kidneys, and liver. Your doctor will monitor these with blood tests.
- Tell your doctor if you have severe kidney disease, liver disease, stomach or bowel disease, or a serious infection (e.g., pneumonia).
- If you think you have shingles, tell your doctor right away.
Show 6 more warnings
- If your MS symptoms worsen or you get new symptoms (e.g., weakness or vision changes), talk to your doctor right away, as these could be signs of a PML infection.
- If you notice you're urinating more, are thirstier, have weak muscles, bone fractures, or pain, talk to your doctor.
- Avoid certain vaccines (live vaccines) while taking this medicine, as they can increase infection risk.
- Avoid strong alcoholic drinks (over 30% alcohol by volume) for one hour before and after taking your dose.
- Do not use this medicine if you are pregnant, unless you have discussed it with your doctor.
- Do not use this medicine while breastfeeding.