Desmopressin Zentiva
This medicine helps your kidneys concentrate urine, which is useful for treating certain conditions like diabetes insipidus, bedwetting in children over 5, and frequent night urination in adults under 65.
How to Use
Dosage
For diabetes insipidus, the usual dose for adults and children is 1-2 tablets (60 microgram) under the tongue three times a day. For bedwetting in children, it's 1-2 tablets (120 microgram) under the tongue at night. For night urination in adults, it's 1 tablet (60 microgram) under the tongue at night.
Method
Place the tablet under your tongue, where it will dissolve without water. Always take it at the same time relative to meals.
Your doctor will determine your exact dose. For bedwetting and night urination, restrict fluid intake from 1 hour before to 8 hours after taking the medicine.
Possible Side Effects
- •Headache
- •Low blood sodium
- •Dizziness
- •High blood pressure
- •Abdominal pain
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Bladder and urinary tract symptoms
- •Swelling in hands, arms, or feet
- •Tiredness
- •Difficulty sleeping
- •Drowsiness
- •Tingling sensation
- •Impaired vision
- •Vertigo (spinning sensation)
- •Palpitations (feeling your heartbeat)
- •Low blood pressure when standing up
- •Shortness of breath
- •Stomach problems (indigestion, gas, bloating)
- •Sweating
- •Itching
- •Rash
- •Hives
- •Muscle cramps
- •Muscle pain
- •Chest pain
- •Flu-like symptoms
- •Weight gain
- •Increased liver enzymes
- •Low blood potassium
- •Confusion
- •Allergic skin rash
- •Anaphylactic reaction (severe allergic allergy)
- •Dehydration
- •High blood sodium
- •Seizures
- •Weakness
- •Coma
- •Emotional changes
- •Aggression
- •Anxiety
- •Nightmares
- •Mood swings
- •Irritability
- •Abnormal behavior
- •Emotional disorders
- •Depression
- •Hallucinations
- •Reduced attention
- •Psychomotor hyperactivity (restlessness, increased movement)
- •Nosebleed
Important Warnings
- Do not take if you are allergic to desmopressin or any other ingredient in this medicine.
- It is important to restrict your fluid intake from 1 hour before taking the medicine until 8 hours after, especially for bedwetting or night urination.
- Contact your doctor immediately if you experience headache, nausea, vomiting, weight gain, confusion, or seizures, as these can be signs of low blood sodium.
- Do not take this medicine if you have severe kidney problems, very strong thirst (polydipsia), heart failure, or certain hormone disorders (SIADH).
- Do not use for night urination if you are over 65 years old or for bedwetting if your child is under 5 years old.
Show 1 more warnings
- Discuss with your doctor if you have coronary artery disease, high blood pressure, thyroid or adrenal gland diseases, or conditions causing fever, vomiting, or diarrhea.
Use in Elderly Patients
Avoid use in older adults. Risk of fluid retention and hyponatraemia. Treatment of ADH deficiency can be started under specialist supervision. (updated 6.11.2023)