Desmopressin Zentiva
This medicine helps your body control how much water it keeps, treating conditions like too much thirst, bedwetting, and needing to pee often at night.
How to Use
Dosage
For diabetes insipidus, adults and children typically take 1-2 tablets (60 micrograms) under the tongue three times a day. For bedwetting in children, it's usually 1-2 tablets (120 micrograms) under the tongue at night. For night-time urination in adults, it's usually 1 tablet (60 micrograms) under the tongue at night. Your doctor will tell you your exact dose.
Method
Place the tablet under your tongue. It will dissolve there without needing water. Always take it at the same time each day, relative to meals. For bedwetting and night-time urination, limit how much you drink for 1 hour before and 8 hours after taking the medicine. Drink only enough to quench your thirst.
Taking too much of this medicine can cause too much fluid to build up in your body and low sodium in your blood, which can be dangerous. Always follow your doctor's instructions carefully.
Possible Side Effects
- •Headache
- •Low blood sodium
- •Dizziness
- •High blood pressure
- •Stomach ache
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Bladder and urinary tract issues
- •Swelling in hands, arms, feet, or legs
- •Tiredness
- •Mood changes
- •Aggression
- •Difficulty sleeping / Trouble sleeping
- •Drowsiness
- •Tingling sensations
- •Vision problems
- •Feeling dizzy (vertigo)
- •Feeling your heart beat
- •Low blood pressure when standing up
- •Shortness of breath
- •Stomach upset (indigestion, gas, bloating)
- •Sweating
- •Itching
- •Rash
- •Hives
- •Muscle cramps
- •Muscle pain
- •Chest pain
- •Flu-like symptoms
- •Weight gain
- •Increased liver enzymes
- •Low blood potassium
- •Confusion
- •Allergic skin rash
- •Severe allergic reaction
- •Dehydration
- •Seizures
- •Weakness
- •Coma
- •Anxiety
- •Nightmares
- •Irritability
- •Unusual behavior
- •Seeing things that aren't there (hallucinations)
- •Reduced attention
- •Increased movement (psychomotor hyperactivity)
- •Nosebleeds
- •Depression
Important Warnings
- Do not take this medicine if you are allergic to desmopressin or any other ingredients.
- Do not take this medicine if you have extreme thirst, heart failure, or other conditions that require medicines to remove fluids (diuretics).
- Do not take this medicine if you have moderate to severe kidney problems.
- Do not take this medicine if you have low sodium levels in your blood.
- Do not take this medicine if you cannot limit your fluid intake as instructed.
Show 7 more warnings
- Do not take this medicine if you have a hormone disorder called SIADH.
- Do not take this medicine if you are over 65 years old and have night-time urination.
- Do not give this medicine to children under 5 years old for bedwetting.
- Talk to your doctor before taking this medicine if you have heart problems (like coronary artery disease or high blood pressure), or problems with your thyroid or adrenal glands.
- If you get a fever, start vomiting, or have diarrhea while taking this medicine, tell your doctor right away.
- If you get headaches, feel very sick (nausea/vomiting), gain weight, feel confused, or have seizures, these could be signs of low sodium in your blood. Stop taking the medicine, drink less, and call your doctor right away.
- Talk to your doctor before taking this medicine if you are at risk for increased pressure in your head.
Use in Elderly Patients
Avoid use in older adults. Risk of fluid retention and hyponatraemia. Treatment of ADH deficiency can be started under specialist supervision. (updated 6.11.2023)