Desmopressin Orifarm
Desmopressin Orifarm helps your kidneys control how much water your body loses, reducing urine output and treating conditions like diabetes insipidus, bedwetting, and frequent night-time urination.
How to Use
Dosage
For central diabetes insipidus, adults and children usually take 60-120 micrograms under the tongue three times a day. For bedwetting in children (5 years and older), take 120-240 micrograms under the tongue at night. For adults with frequent night-time urination, start with 60 micrograms under the tongue at night; this dose can be increased weekly to 120 then 240 micrograms if needed.
Method
Place the tablet under your tongue, where it will dissolve without water. Do not chew or swallow it whole.
Limit your fluid intake as much as possible for 1 hour before and 8 hours after taking the medicine, especially for bedwetting and frequent night-time urination. Taking with food may reduce its effect.
Possible Side Effects
- •Headache
- •Low sodium levels in blood
- •Dizziness
- •High blood pressure (more common in adults)
- •Nausea
- •Stomach pain
- •Diarrhea
- •Constipation (in adults)
- •Vomiting
- •Bladder and urinary tract symptoms
- •Swelling (e.g., swollen hands and feet in children)
- •Tiredness
- •Trouble sleeping (insomnia)
- •Drowsiness
- •Tingling sensations (in adults)
- •Blurred vision (in adults)
- •Spinning sensation (vertigo, in adults)
- •Fast or pounding heartbeat (in adults)
- •Dizziness or lightheadedness when standing up (in adults)
- •Shortness of breath (in adults)
- •Indigestion (in adults)
- •Gas and bloating in the stomach (in adults)
- •Sweating
- •Itching
- •Skin rash
- •Hives (itchy red welts)
- •Muscle cramps
- •Muscle pain (in adults)
- •General feeling of being unwell (in adults)
- •Chest pain (in adults)
- •Flu-like symptoms (in adults)
- •Weight gain (in adults)
- •Increased liver enzyme levels in blood (in adults)
- •Low potassium levels in blood (in adults)
- •Confusion (in adults)
- •Allergic skin rash
- •Severe allergic reaction (anaphylactic reaction)
- •Dehydration (in adults)
- •High sodium levels in blood (hypernatremia, in adults)
- •Seizures
- •Weakness (in adults)
- •Coma (in adults)
- •Mood swings or unstable emotions (more common in children)
- •Aggression (more common in children)
- •Anxiety symptoms (more common in children)
- •Nightmares (more common in children)
- •Irritability (more common in children)
- •Abnormal behavior (more common in children)
- •Emotional disorders (more common in children)
- •Depression (more common in children)
- •Seeing or hearing things that aren't there (hallucinations, more common in children)
- •Trouble paying attention (attention deficit, more common in children)
- •Increased muscle movements (psychomotor hyperactivity, more common in children)
- •Nosebleeds (more common in children)
Important Warnings
- Do not take if you are allergic to desmopressin or any other ingredient in this medicine.
- Do not take if you have extreme thirst and drink too much fluid.
- Do not take if you have or might have heart failure.
- Do not take if you have other conditions that need treatment with water pills (diuretics).
- Do not take if you have moderate to severe kidney problems.
Show 7 more warnings
- Do not take if you have low sodium levels in your blood.
- Do not take if you have a hormone disorder called SIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion).
- Talk to your doctor if you have severe bladder problems or difficulty urinating.
- Talk to your doctor if you are 65 or older and have low blood sodium or pass a lot of urine daily.
- Talk to your doctor if you are at risk of increased pressure in your head.
- Talk to your doctor if you have a medical condition causing problems with your body's fluid or salt balance.
- Talk to your doctor if you are taking other medicines at the same time.