Desmopressin Orifarm
Desmopressin Orifarm mimics a natural hormone to help your kidneys control the amount of urine your body makes, often used for conditions like bedwetting or frequent night-time urination.
How to Use
Dosage
Your doctor will tell you your exact dose. For central diabetes insipidus, adults and children usually take 60-120 micrograms under the tongue three times a day. For children aged 5 and older with bedwetting, it's typically 120-240 micrograms under the tongue at night. For adults with frequent night-time urination (nocturia), the starting dose is 60 micrograms under the tongue at night, which can be increased up to 240 micrograms.
Method
Place the tablet under your tongue. It will dissolve there without water. Do not take it with food, as this might make the medicine less effective.
Do not take more than 240 micrograms as a single dose. For bedwetting and frequent night-time urination, limit your fluid intake as instructed by your doctor, especially 1 hour before and 8 hours after taking the medicine.
Possible Side Effects
- •Headache
- •Low sodium in blood (can cause dizziness, confusion, or seizures)
- •Dizziness
- •High blood pressure
- •Nausea (feeling sick)
- •Stomach pain
- •Diarrhea
- •Constipation
- •Vomiting (being sick)
- •Problems with bladder and urinary tract
- •Swelling (e.g., in hands and feet)
- •Tiredness
- •Mood swings, aggression (especially in children)
- •Anxiety, nightmares
- •Trouble sleeping (insomnia), sleepiness
- •Tingling or numbness
- •Vision problems, spinning sensation (vertigo)
- •Fast or irregular heartbeat
- •Dizziness when standing up (low blood pressure)
- •Shortness of breath
- •Indigestion, gas, bloated stomach
- •Sweating, itching, skin rash, hives, allergic skin reaction
- •Muscle cramps or pain
- •Feeling unwell, chest pain, flu-like symptoms
- •Weight gain
- •Changes in blood tests (e.g., liver enzymes or potassium)
- •Confusion
- •Severe allergic reaction (anaphylaxis)
- •Dehydration, high sodium in blood
- •Seizures, coma
- •Abnormal behavior, depression, hallucinations, attention problems, hyperactivity, nosebleeds (especially in children)
Important Warnings
- Do not use this medicine if you are allergic to desmopressin or any other ingredient in it.
- Do not use if you drink too much liquid, have strong thirst, or have heart problems.
- Do not use if you have severe kidney problems, low sodium in your blood, or a hormone problem called SIADH.
- Talk to your doctor before using if you have severe bladder issues, are 65 or older with low blood sodium, or have a risk of increased pressure in your head.
- Tell your doctor about all other medicines you are taking, as some can affect this medicine.