Darunavir Sandoz
Darunavir Sandoz is an antiviral medicine used to treat HIV infection by lowering the amount of HIV in your body, which helps your immune system and reduces the risk of HIV-related illnesses.
Form
tabletti, kalvopäällysteinen
Strength
800 mg
Active Ingredient
Darunavir
Manufacturer
Sandoz A/S
How to Use
Dosage
The usual dose is one 800 mg Darunavir Sandoz tablet (or two 400 mg tablets) once a day.
Method
Take your tablet(s) once a day with food, along with 150 mg of cobicistat or 100 mg of ritonavir. You must eat a meal or snack no more than 30 minutes before taking this medicine. Swallow the tablet(s) with a drink like water or milk.
Important
The maximum daily dose is 800 mg, taken once a day.
Possible Side Effects
COMMON
- •Diarrhea
- •Vomiting
- •Nausea
- •Stomach pain or bloating
- •Indigestion
- •Gas
- •Headache
- •Fatigue
- •Dizziness
- •Drowsiness
- •Numbness, tingling, or pain in hands or feet
- •Weakness
- •Difficulty sleeping
RARE
- •Chest pain, changes in heart rhythm (ECG), fast heartbeat
- •Changes in skin sensation, tingling, difficulty concentrating, memory loss, balance problems
- •Breathing difficulties, cough, nosebleeds, throat irritation
- •Stomach or mouth inflammation, heartburn, dry mouth, abdominal discomfort, constipation, burping, gagging
- •Kidney problems (kidney failure, kidney stones, difficulty or frequent urination)
- •Hives, severe swelling of skin (lips or eyes), eczema, excessive sweating (including night sweats), hair loss, acne, flaky skin, discolored nails
- •Muscle pain, cramps or weakness, limb pain, bone weakening (osteoporosis)
- •Underactive thyroid gland (shown in blood tests)
- •High blood pressure, flushing
- •Red or dry eyes
- •Fever, leg swelling due to fluid retention, general unwell feeling, irritability, pain, infection symptoms (like herpes simplex)
- •Erectile dysfunction, breast enlargement in men
- •Sleep problems, drowsiness, depression, anxiety, abnormal dreams, reduced sex drive
- •Severe allergic reaction called DRESS (rash, fever, fatigue, swollen face or lymph nodes, changes in blood cells, effects on liver, kidneys, or lungs)
- •Heart attack, slow or fast heartbeat, palpitations
- •Vision problems
- •Chills, feeling unwell
- •Confusion, mood changes, restlessness
- •Fainting, seizures (epileptic attacks), changes or loss of taste
- •Mouth sores, vomiting blood, lip inflammation, dry lips, coated tongue
- •Runny nose
- •Skin damage, dry skin
- •Stiff muscles or joints, joint pain (with or without inflammation)
- •Darunavir crystals in the kidneys causing kidney disease
Important Warnings
- Do not take this medicine if you are allergic to darunavir, cobicistat, ritonavir, or any other ingredients, or if you have severe liver disease.
- This medicine does not cure HIV infection; you must continue seeing your doctor regularly.
- Skin rash can occur, sometimes severe. Contact your doctor immediately if you develop a rash.
- Inform your doctor if you have had liver problems, including Hepatitis B or C, as this medicine can affect your liver.
- This medicine may increase blood sugar levels. Tell your doctor if you have diabetes.
Show 6 more warnings
- If you have a bleeding disorder (like haemophilia), this medicine might increase your risk of bleeding.
- Inform your doctor if you are allergic to sulfonamides.
- Report any muscle or bone problems to your doctor.
- Do not drive or use machines if you feel dizzy after taking this medicine.
- Do not stop taking this medicine without talking to your doctor first, even if you feel better.
- Do not use this medicine with products containing St. John's Wort.