Daptomycin Reddy
Daptomycin Reddy is an antibiotic used to treat serious bacterial infections of the skin, blood, and heart in adults and children.
Form
injektio/infuusiokuiva-aine, liuosta varten
Strength
500 mg
Active Ingredient
Daptomycin
Manufacturer
Reddy Holding GmbH
How to Use
Dosage
For skin infections, 4 mg per kg of body weight once daily; for heart or blood infections, 6 mg per kg of body weight once daily.
Method
The medicine is given directly into a vein as an infusion over about 30 minutes or as an injection over about 2 minutes.
Important
The maximum daily dose is 4 mg/kg for skin infections and 6 mg/kg for heart or blood infections, given once daily.
Possible Side Effects
COMMON
- •Fungal infections, such as thrush.
- •Urinary tract infections.
- •Decrease in red blood cells (anemia).
- •Dizziness, anxiety, difficulty sleeping.
- •Headache.
- •Fever, weakness.
- •High or low blood pressure.
- •Constipation, abdominal pain.
- •Diarrhea, nausea or vomiting.
- •Flatulence.
- •Abdominal swelling or bloating.
- •Rashes or itching.
- •Pain, itching, or redness at the injection site.
- •Pain in hands/arms or legs.
- •Higher than normal liver enzyme levels or creatine phosphokinase (CPK) values in blood tests.
RARE
- •Blood disorders (e.g., increased platelets, increased white blood cell types).
- •Decreased appetite.
- •Tingling or numbness in hands or feet, changes in taste.
- •Tremors.
- •Changes in heart rhythm, flushing.
- •Indigestion (dyspepsia), tongue inflammation.
- •Itchy skin rash.
- •Muscle pain, cramps or weakness, muscle inflammation (myositis), joint pain.
- •Kidney problems.
- •Vaginal inflammation or irritation.
- •General pain or weakness, fatigue.
- •Increased blood sugar, serum creatinine, myoglobin, or lactate dehydrogenase (LDH) levels in blood tests, prolonged blood clotting time, or electrolyte imbalances.
- •Itchy eyes.
- •Yellowing of skin or eyes (jaundice).
- •Prolonged prothrombin time (blood clotting time).
- •Colitis associated with antibiotic use (severe or prolonged diarrhea with blood/mucus, abdominal pain, fever).
- •Increased bruising.
- •Bleeding gums.
- •Nosebleeds.
Important Warnings
- Do not take Daptomycin Reddy if you are allergic to daptomycin, sodium hydroxide, or any other ingredients in this medicine.
- Tell your doctor if you have or have had kidney problems, as your dose may need to be changed.
- Tell your doctor if you experience muscle tenderness, pain, or weakness. Your doctor may need to do blood tests.
- Inform your doctor if you have ever had a severe skin rash, peeling skin, blisters, mouth sores, or serious kidney problems after using daptomycin.
- If you are very overweight, your doctor will watch you closely for side effects, as the medicine might stay in your blood longer.
Show 12 more warnings
- Get immediate medical help if you have signs of a severe allergic reaction, such as wheezing, trouble breathing, swelling of the face, neck or throat, rash, hives, or fever.
- Tell your doctor right away if you develop severe skin conditions with symptoms like fever, red raised or fluid-filled spots, or blisters/sores in your mouth or genital area.
- Tell your doctor if you get new symptoms of severe kidney problems, such as fever and rash.
- Tell your doctor if you have unusual tingling or numbness in your hands and feet, loss of sensation, or trouble moving.
- Report diarrhea, especially if it has blood or mucus, or if it becomes severe or lasts a long time.
- Tell your doctor if you have fever, worsening fever, cough, or trouble breathing, as these could be signs of a rare but serious lung condition.
- Daptomycin Reddy may affect blood clotting tests, so tell your doctor you are taking this medicine before any blood tests.
- Daptomycin Reddy should not be given to children under 1 year old.
- Do not breastfeed while taking Daptomycin Reddy, as the medicine can pass into breast milk and affect the baby.
- Tell your doctor about all other medicines you are taking, especially cholesterol-lowering drugs (statins or fibrates) or ciclosporin, as combining them with Daptomycin Reddy can increase the risk of muscle problems.
- Tell your doctor if you are taking NSAIDs or COX-2 inhibitors (like celecoxib), as they can affect how Daptomycin Reddy works on your kidneys.
- Tell your doctor if you are taking blood thinners (like warfarin), as your doctor may need to monitor your blood clotting time.