Daptomycin Noridem
Daptomycin Noridem is an antibiotic used to treat serious skin, bloodstream, and heart infections in adults and children.
Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
500 mg
Active Ingredient
Daptomycin
Manufacturer
Noridem Enterprises Limited
How to Use
Dosage
Adults usually receive 4 mg per kilogram of body weight once daily for skin infections, or 6 mg per kilogram once daily for bloodstream or heart infections.
Method
The medicine is given directly into a vein. For adults, it is given as an infusion over about 30 minutes or as an injection over about 2 minutes. For children and adolescents, it is always given as an infusion over 30-60 minutes.
Important
Your doctor will decide your daily dose based on your weight and the type of infection; it is given once a day.
Possible Side Effects
COMMON
- •Fungal infections, such as thrush
- •Urinary tract infection
- •Reduced red blood cells (anemia)
- •Dizziness, anxiety, trouble sleeping
- •Headache
- •Fever, weakness (asthenia)
- •High or low blood pressure
- •Constipation, abdominal pain
- •Diarrhea, nausea or vomiting
- •Flatulence
- •Abdominal swelling or bloating
- •Rashes or itching
- •Pain, itching, or redness at the injection site
- •Pain in arms or legs
- •Higher levels of liver enzymes or creatine phosphokinase (CPK) in blood tests
RARE
- •Blood disorders (e.g., increased platelets or white blood cells)
- •Decreased appetite
- •Tingling or numbness in hands or feet, altered taste
- •Tremors
- •Changes in heart rhythm, flushing
- •Indigestion (dyspepsia), tongue inflammation
- •Itchy skin rash
- •Muscle pain, cramps or weakness, muscle inflammation (myositis), joint pain
- •Kidney disorders
- •Vaginal inflammation or irritation
- •General pain or weakness, fatigue
- •High blood sugar, creatinine, myoglobin, or LDH in blood tests; prolonged blood clotting time; electrolyte imbalances
- •Itchy eyes
- •Yellowing of skin and whites of eyes (jaundice)
- •Prolonged prothrombin time (blood clotting time)
- •Antibiotic-related colitis, including severe or prolonged diarrhea with blood or mucus, stomach pain, or fever
- •Easy bruising, bleeding gums, or nosebleeds
Important Warnings
- Do not take this medicine if you are allergic to daptomycin or any other ingredients.
- Tell your doctor if you have kidney problems, as your dose might need to be adjusted.
- Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately.
- Seek immediate medical help if you experience severe allergic reactions like wheezing, trouble breathing, swelling of your face/neck/throat, rash, hives, or fever.
- Tell your doctor right away if you develop severe skin reactions, including fever, red raised or fluid-filled spots, blisters, or sores in your mouth or genitals.
Show 8 more warnings
- Inform your doctor about new or worsening fever, cough, or trouble breathing, as these could be signs of a rare lung condition.
- Report any unusual tingling, numbness, loss of sensation, or difficulty moving your hands and feet.
- Tell your doctor if you experience severe or prolonged diarrhea, especially if it contains blood or mucus.
- This medicine can affect blood clotting test results, making it seem like your blood doesn't clot well, even if it does. Inform your doctor you are taking Daptomycin Noridem.
- Tell your doctor if you are taking cholesterol-lowering medicines (statins or fibrates) or cyclosporine, as this medicine might increase your risk of muscle problems.
- Inform your doctor if you are taking NSAIDs or COX-2 inhibitors (painkillers), as they can affect how Daptomycin Noridem works in your kidneys.
- If you are taking blood thinners (anticoagulants like warfarin), your doctor might need to monitor your blood clotting time more closely.
- This medicine is generally not given to pregnant women. Do not breastfeed while taking this medicine, as it can pass into breast milk.