Daptomycin MIP Pharma

Daptomycin MIP Pharma is an antibiotic used to treat severe skin, blood, and heart infections caused by certain bacteria.

Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
350 mg
Active Ingredient
Daptomycin
Manufacturer
MIP Pharma GmbH

How to Use

Dosage

For adults, 4 mg per kg of body weight for skin infections or 6 mg per kg for heart or bloodstream infections, once a day. For children, the dose depends on their age and the type of infection.

Method

The medicine is given directly into a vein, either as about a 30-minute infusion or a 2-minute injection for adults. For children, it is given as a 30-60 minute infusion.

Important

Usually once a day, but your doctor may adjust the dose if you have kidney problems.

Possible Side Effects

COMMON
  • •Fungal infections, such as thrush
  • •Urinary tract infections
  • •Reduced red blood cells (anemia)
  • •Dizziness, anxiety, trouble sleeping
  • •Headache
  • •Fever, weakness
  • •High or low blood pressure
  • •Constipation, abdominal pain
  • •Diarrhea, nausea or vomiting
  • •Gas
  • •Abdominal swelling or bloating
  • •Rashes or itching
  • •Pain, itching or redness at the infusion site
  • •Pain in hands/arms or legs
  • •Higher liver enzymes or CPK levels in blood tests
RARE
  • •Blood disorders that increase clotting tendency or increase certain white blood cells
  • •Decreased appetite
  • •Tingling or numbness in hands/feet, changes in taste
  • •Tremor
  • •Heart rhythm changes, flushing
  • •Indigestion, tongue inflammation
  • •Itchy rash
  • •Muscle pain, cramps, or weakness, muscle inflammation (myositis), joint pain
  • •Kidney problems
  • •Vaginal inflammation or irritation
  • •General pain or weakness, fatigue
  • •High blood sugar, creatinine, myoglobin, or LDH levels in blood tests, prolonged blood clotting time, or electrolyte imbalance
  • •Itchy eyes
  • •Yellowing of skin or eyes
  • •Prolonged prothrombin time (blood clotting time)
  • •Easy bruising, bleeding gums, or nosebleeds

Important Warnings

  • If you have or have had kidney problems, your doctor may need to change your dose.
  • Tell your doctor immediately if you develop unexplained muscle pain, tenderness, or weakness.
  • Seek immediate medical attention if you experience symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face, or rash.
  • Tell your doctor immediately if you develop fever, rash, blisters, or sores on your skin or in your mouth.
  • Tell your doctor if you develop severe or prolonged diarrhea, especially if it contains blood or mucus.
Show 4 more warnings
  • Inform your doctor if you have fever, cough, or difficulty breathing, as these can be signs of a rare but serious lung disease.
  • Tell your doctor if you experience unusual tingling, numbness, or loss of sensation in your hands or feet.
  • Inform your doctor that you are taking this medicine, as it can affect blood clotting tests.
  • This medicine should not be given to children under 1 year of age.