Daptomycin hameln

Daptomycin hameln is an antibiotic that stops the growth of certain bacteria, used to treat skin, blood, and heart infections.

Form
injektio/infuusiokuiva-aine, liuosta varten
Strength
500 mg
Active Ingredient
Daptomycin
Manufacturer
Hameln Pharma GmbH

How to Use

Dosage

For adults, 4 mg per kg once daily for skin infections, or 6 mg per kg once daily for heart or blood infections. For children (1-17 years), dosage depends on age and infection type, as determined by your doctor.

Method

Adults receive the dose directly into a vein as a 30-minute infusion or a 2-minute injection. Children (1-17 years) receive it as a 30-60 minute infusion into a vein.

Important

For adults, the maximum daily dose is 4 mg/kg or 6 mg/kg once daily, depending on the infection. For children, it varies by age and infection type. Your doctor will determine the appropriate dose.

Possible Side Effects

COMMON
  • Fungal infections (e.g., thrush)
  • Urinary tract infections
  • Decrease in red blood cells (anemia)
  • Dizziness
  • Anxiety
  • Trouble sleeping (insomnia)
  • Headache
  • Fever
  • Feeling weak (asthenia)
  • High or low blood pressure
  • Constipation
  • Abdominal pain
  • Diarrhea
  • Nausea or vomiting
  • Flatulence (gas)
  • Abdominal swelling or bloating
  • Rashes or itching
  • Pain, itching, or redness at the injection site
  • Pain in hands/arms or legs
  • Abnormally high liver enzymes or creatine phosphokinase (CPK) in blood tests
RARE
  • Blood disorders (e.g., increased platelets or certain white blood cells)
  • Loss of appetite
  • Tingling or numbness in hands or feet
  • Taste disturbances
  • Tremor
  • Changes in heart rhythm
  • Flushing
  • Indigestion (dyspepsia)
  • Tongue inflammation
  • Itchy rash
  • Muscle pain, cramps, or weakness
  • Muscle inflammation (myositis)
  • Joint pain
  • Kidney problems
  • Vaginal inflammation or irritation
  • General pain or weakness, fatigue
  • Increased blood sugar, serum creatinine, myoglobin, or lactate dehydrogenase in blood tests
  • Prolonged blood clotting time or electrolyte imbalance
  • Itchy eyes
  • Yellowing of the skin or whites of the eyes
  • Prolonged prothrombin time (blood clotting time)

Important Warnings

  • Do not take if you are allergic to daptomycin, sodium hydroxide, or any other ingredient in this medicine.
  • Tell your doctor immediately if you experience muscle pain, tenderness, or weakness, as this could be a serious side effect.
  • Seek immediate medical attention if you have signs of a severe allergic reaction, such as wheezing, difficulty breathing, swelling of the face, neck or throat, rash, hives, or fever.
  • Inform your doctor if you have or have had kidney problems, as your dose may need to be adjusted.
  • Consult your doctor if you develop a severe skin rash with fever, blisters, or peeling, or if you have severe kidney problems after taking this medicine.
Show 3 more warnings
  • Tell your doctor if you are significantly overweight, as Daptomycin hameln levels in your blood might be higher, requiring close monitoring for side effects.
  • Do not use Daptomycin hameln in children under 1 year of age due to potential severe side effects.
  • This medicine is generally not given to pregnant women. Do not breastfeed if you are receiving Daptomycin hameln, as the medicine may pass into breast milk.