Daptomycin Advanz Pharma

Daptomycin Advanz Pharma is an antibiotic used to treat serious skin, blood, and heart infections in adults and children.

Form
injektio/infuusiokuiva-aine, liuosta varten
Strength
500 mg
Active Ingredient
Daptomycin
Manufacturer
Advanz Pharma Limited

How to Use

Dosage

The dose depends on your weight, age, and the type of infection; for adults, it's usually 4-6 mg per kilogram of body weight.

Method

The medicine is given directly into a vein: for adults, either as a 30-minute infusion or a 2-minute injection; for children and adolescents (1-17 years), as a 30-60 minute infusion.

Important

The medicine is usually given once a day.

Possible Side Effects

COMMON
  • •Fungal infections, like thrush
  • •Urinary tract infections
  • •Decrease in red blood cells (anemia)
  • •Dizziness
  • •Anxiety
  • •Trouble sleeping
  • •Headache
  • •Fever
  • •Feeling weak (asthenia)
  • •High or low blood pressure
  • •Constipation
  • •Stomach pain
  • •Diarrhea
  • •Nausea or vomiting
  • •Gas
  • •Bloating or swollen abdomen
  • •Rash or itching
  • •Pain, itching or redness at the injection site
  • •Pain in hands/arms or legs
  • •Higher than normal liver enzyme levels in blood tests
  • •Higher than normal creatine phosphokinase (CPK) levels in blood tests
RARE
  • •Blood disorders (e.g., increased platelets, which can raise blood clotting tendency, or increased certain white blood cell types)
  • •Decreased appetite
  • •Tingling or numbness in hands or feet
  • •Changes in taste
  • •Tremor
  • •Changes in heart rhythm
  • •Flushing
  • •Indigestion (dyspepsia)
  • •Tongue inflammation
  • •Itchy rash
  • •Muscle pain, cramps or weakness
  • •Muscle inflammation (myositis)
  • •Joint pain
  • •Kidney disorders
  • •Vaginal inflammation or irritation
  • •General pain or weakness
  • •Tiredness (fatigue)
  • •Increased blood sugar levels in blood tests
  • •Increased serum creatinine levels in blood tests
  • •Increased myoglobin levels in blood tests
  • •Increased lactate dehydrogenase (LDH) levels in blood tests
  • •Prolonged blood clotting time
  • •Electrolyte imbalances
  • •Itchy eyes
  • •Yellowing of skin or whites of eyes
  • •Prolonged prothrombin time (blood clotting time)
  • •Colitis associated with antibiotics (severe or prolonged diarrhea with blood/mucus, stomach pain or fever)
  • •Increased bruising
  • •Bleeding gums or nosebleeds

Important Warnings

  • Do not use this medicine if you are allergic to daptomycin or any other ingredient.
  • Tell your doctor if you have or have had kidney problems, as your dose may need to be adjusted.
  • Tell your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness.
  • Seek immediate medical attention if you develop fever, rash, blisters, or sores in your mouth or genitals.
  • Seek immediate medical attention if you experience shortness of breath, facial swelling, rash, or fever, which could be signs of a severe allergic reaction.
Show 5 more warnings
  • Tell your doctor if you have fever, cough, or difficulty breathing, as these could be signs of a rare lung condition.
  • Inform your doctor that you are taking this medicine, as it can affect blood clotting test results.
  • This medicine should not be given to children under 1 year of age.
  • This medicine is generally not given to pregnant or breastfeeding women. Consult your doctor if you are pregnant or breastfeeding.
  • Tell your doctor about all other medicines you are taking, especially cholesterol-lowering drugs, NSAIDs, and blood thinners.