Daptomycin Accordpharma
This medicine stops certain bacteria from growing to treat infections of the skin, blood, and heart.
Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
350 mg
Active Ingredient
Daptomycin
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
For skin infections, 4 mg per kg of body weight once daily. For heart or blood infections, 6 mg per kg of body weight once daily.
Method
It is given into your vein by a doctor or nurse. For adults, it's either a slow drip over about 30 minutes or a quick shot over about 2 minutes. For children (1-17 years), it's a slow drip over 30-60 minutes.
Important
The maximum daily dose is the prescribed amount (either 4 mg/kg or 6 mg/kg) given once a day.
Possible Side Effects
COMMON
- •Fungal infections (like thrush)
- •Urinary tract infections
- •Low red blood cell count (anemia)
- •Dizziness
- •Anxiety
- •Trouble sleeping
- •Headache
- •Fever
- •Feeling weak
- •High or low blood pressure
- •Constipation
- •Stomach pain
- •Diarrhea
- •Nausea or vomiting
- •Gas (flatulence)
- •Swollen or bloated stomach
- •Rashes or itching
- •Pain, itching, or redness at the injection site
- •Pain in hands, arms, or legs
- •High levels of liver enzymes or a muscle enzyme (CPK) in blood tests
RARE
- •Blood disorders (e.g., increased platelets or white blood cells)
- •Decreased appetite
- •Tingling or numbness in hands or feet
- •Changes in taste
- •Tremor (shaking)
- •Changes in heart rhythm
- •Flushing (redness)
- •Indigestion
- •Tongue inflammation
- •Itchy skin rash
- •Muscle pain, cramps, or weakness
- •Muscle inflammation
- •Joint pain
- •Kidney problems
- •Vaginal inflammation or irritation
- •General pain or weakness
- •Fatigue (tiredness)
- •Increased blood sugar, serum creatinine, myoglobin, or LDH in blood tests
- •Prolonged blood clotting time
- •Salt imbalance
- •Itchy eyes
- •Yellowing of skin or eyes
- •Prolonged prothrombin time (a blood clotting test result)
Important Warnings
- Do not use this medicine if you are allergic to daptomycin or any other ingredients listed in section 6.
- Tell your doctor if you have or have had kidney problems, as your dose might need to be adjusted.
- Tell your doctor right away if you experience muscle pain, tenderness, or weakness, as blood tests may be needed.
- Seek immediate medical help if you develop severe skin reactions like rashes, peeling skin, blisters, or sores in your mouth or genitals.
- Tell your doctor if you are very overweight, as your blood levels of the medicine might be higher, and you may need closer monitoring.
Show 8 more warnings
- Get urgent medical help if you have sudden, severe allergic reactions, which can include wheezing, trouble breathing, swelling of your face, neck, or throat, rash, hives, or fever.
- Tell your doctor if you experience tingling, numbness, or difficulty moving your hands or feet.
- Report any severe or long-lasting diarrhea, especially if it contains blood or mucus.
- Tell your doctor immediately if you have fever, worsening cough, or trouble breathing, as these could be signs of a rare but serious lung condition.
- This medicine can affect blood clotting tests, so it's important to tell your doctor you are taking Daptomycin Accordpharma.
- Do not give this medicine to children under 1 year old, as animal studies have shown it can cause serious side effects in this age group.
- Do not breastfeed while using this medicine, as it may pass into breast milk and affect the baby.
- Tell your doctor about all other medicines you are taking, especially cholesterol-lowering drugs (statins, fibrates), ciclosporin, pain relievers (NSAIDs, COX-2 inhibitors), and blood thinners (like warfarin), as they can interact with Daptomycin Accordpharma.