Daptomycin Accord Healthcare
Daptomycin Accord Healthcare is an antibiotic used to treat serious skin, blood, and heart infections caused by certain bacteria in adults and children (1-17 years).
Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
350 mg
Active Ingredient
Daptomycin
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
For adults, typically 4 mg per kg for skin infections, or 6 mg per kg for heart/blood infections, once daily.
Method
Given directly into a vein (intravenously) as an infusion over 30 minutes, or a slow injection over 2 minutes (for adults only). For children, it is given as an infusion over 30-60 minutes.
Important
Do not exceed the dose prescribed by your doctor. Your doctor may adjust the dose based on your kidney function.
Possible Side Effects
COMMON
- •Fungal infections (e.g., thrush)
- •Urinary tract infections
- •Low red blood cell count (anemia)
- •Dizziness
- •Anxiety
- •Trouble sleeping
- •Headache
- •Fever
- •Feeling weak
- •High or low blood pressure
- •Constipation
- •Stomach pain
- •Diarrhea
- •Nausea or vomiting
- •Gas
- •Abdominal bloating
- •Skin rash
- •Itching
- •Pain at the injection site
- •Itching at the injection site
- •Redness at the injection site
- •Pain in arms or legs
- •Higher liver enzyme levels (seen in blood tests)
- •Higher CPK levels (seen in blood tests)
RARE
- •Blood disorders (e.g., changes in platelets or white blood cells)
- •Loss of appetite
- •Tingling or numbness in hands or feet
- •Changes in taste
- •Tremors
- •Changes in heart rhythm
- •Flushing (redness of skin)
- •Indigestion
- •Tongue inflammation
- •Itchy skin rash
- •Muscle pain
- •Muscle cramps
- •Muscle weakness
- •Muscle inflammation (myositis)
- •Joint pain
- •Kidney problems
- •Vaginal inflammation or irritation
- •General pain
- •General weakness
- •Tiredness (fatigue)
- •Increased blood sugar (seen in blood tests)
- •Increased creatinine, myoglobin, or LDH levels (seen in blood tests)
- •Prolonged blood clotting time (seen in blood tests)
- •Electrolyte imbalance (seen in blood tests)
- •Itchy eyes
- •Yellowing of skin or whites of eyes
- •Severe or prolonged diarrhea with blood and/or mucus, abdominal pain, or fever (antibiotic-associated colitis)
- •Easy bruising
- •Bleeding gums or nosebleeds
Important Warnings
- If you have kidney problems, your doctor may need to adjust your dose; severe kidney issues might cause fever and rash. Always inform your doctor about kidney concerns.
- Tell your doctor right away if you have unexplained muscle pain, tenderness, or weakness. Your doctor will check your blood with tests.
- Seek emergency medical help immediately if you experience signs of a severe allergic reaction (such as trouble breathing, swelling of your face or throat, rash, hives, or a fast/weak heartbeat) or severe skin reactions (like widespread rash, peeling skin, blisters, or sores in your mouth or genitals, with or without fever).
- Inform your doctor if you develop new or worsening fever, cough, or trouble breathing, as these could be symptoms of a rare, serious lung condition.
- Tell your doctor if you feel tingling, numbness, or weakness in your hands or feet.
Show 4 more warnings
- Report severe or persistent diarrhea, especially if it contains blood or mucus, to your doctor.
- If you are very overweight, your doctor will monitor you closely for side effects.
- This medicine can affect blood clotting test results, so always inform your doctor you are taking Daptomycin Accord Healthcare.
- Do not give this medicine to children under 1 year old.