Dapagliflozin/Metformin Krka
Dapagliflozin/Metformin Krka is a medicine for type 2 diabetes that helps lower blood sugar by removing excess sugar through urine and reducing sugar production in the liver.
Form
tabletti, kalvopäällysteinen
Strength
5 mg / 1000 mg
Active Ingredient
Dapagliflozin propanediol monohydrate
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual dose is one tablet twice a day.
Method
Swallow the tablet whole with half a glass of water, with food in the morning and in the evening to avoid stomach problems.
Important
Do not take more than the dose your doctor prescribed (usually two tablets daily) to prevent overdose.
Possible Side Effects
COMMON
- •Nausea, vomiting, diarrhea, stomach pain, or loss of appetite.
- •Low blood sugar (hypoglycemia), especially when used with insulin or other diabetes medicines.
- •Genital infections (thrush) causing irritation, itching, or unusual discharge/smell.
- •Discomfort when urinating, increased urine volume, or needing to urinate more often.
- •Back pain.
- •Changes in blood cholesterol or fat levels (shown in lab tests).
- •Increased red blood cell count (shown in lab tests).
- •Decreased kidney function (creatinine clearance) at the start of treatment.
- •Changes in taste.
- •Dizziness.
- •Rash.
- •Low vitamin B12 levels in blood, possibly causing extreme tiredness, sore tongue, tingling, or pale/yellow skin.
RARE
- •Dehydration (losing too much body water), signs include very dry mouth, little or no urine, or fast heartbeat.
- •Thirst.
- •Constipation.
- •Waking up at night to urinate.
- •Dry mouth.
- •Weight loss.
- •Increased blood creatinine and urea levels at the start of treatment (shown in lab tests).
- •Abnormal liver function tests or liver inflammation (hepatitis).
- •Skin redness, itching, or hives.
- •Kidney inflammation (tubulointerstitial nephritis).
Important Warnings
- Do not take this medicine if you are allergic to dapagliflozin, metformin, or any other ingredient, or if you have a history of diabetic coma.
- Stop taking immediately and get medical help if you develop symptoms of lactic acidosis (severe nausea, vomiting, stomach pain, muscle cramps, extreme tiredness, or trouble breathing), as this can lead to coma.
- Seek immediate medical help if you develop symptoms of diabetic ketoacidosis (high ketone levels in urine/blood, rapid weight loss, nausea, vomiting, stomach pain, strong thirst, fast and deep breathing, confusion, unusual sleepiness, sweet-smelling breath, or metallic taste in mouth).
- Contact your doctor right away if you experience symptoms of Fournier's gangrene (pain, tenderness, redness, or swelling in genitals or anal area with fever or general unwellness).
- Talk to your doctor if you have severe kidney, liver, or heart problems, severe infection, or if you drink a lot of alcohol.
Show 1 more warnings
- Inform your doctor if you have signs of dehydration (very dry mouth, little or no urine, fast heart rate) or very low blood sugar (shaking, sweating, fast heartbeat, hunger, headache, confusion), especially if also taking insulin or sulfonylurea.