Dapagliflozin Krka
Dapagliflozin Krka helps lower blood sugar and is used to treat type 2 diabetes, heart failure, and chronic kidney disease.
Form
tabletti, kalvopäällysteinen
Strength
5 mg
Active Ingredient
Dapagliflozin propanediol monohydrate
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual dose is one 10 mg tablet once daily; your doctor may start you on a 5 mg dose if you have liver problems.
Method
Swallow the tablet whole or divided with water, with or without food, preferably at the same time each day.
Important
Do not exceed one 10 mg tablet per day.
Possible Side Effects
COMMON
- •Low blood sugar (hypoglycemia) (shaking, sweating, intense anxiety, fast heartbeat, hunger, headache, changes in vision, mood changes, confusion)
- •Genital infection (yeast infection) of the penis or vagina (irritation, itching, abnormal discharge or smell)
- •Back pain
- •Increased urine output or more frequent urination
- •Changes in cholesterol or fat levels (seen in lab tests)
- •Increase in red blood cells in the blood (seen in lab tests)
- •Decreased kidney function (creatinine clearance) at the start of treatment (seen in lab tests)
- •Dizziness
- •Rash
RARE
- •Swelling of face, tongue, or throat; difficulty swallowing; hives; difficulty breathing (angioedema)
- •Diabetic ketoacidosis (high ketone levels, nausea, vomiting, stomach pain, intense thirst, rapid or deep breathing, confusion, unusual sleepiness or tiredness, sweet-smelling breath, sweet or metallic taste in mouth, change in urine or sweat smell, rapid weight loss)
- •Severe infection of the soft tissue in the genital or anal area (Fournier's gangrene)
- •Too much fluid loss from your body (dehydration) (very dry or sticky mouth, urinating little or not at all, or fast heartbeat)
- •Thirst
- •Constipation
- •Waking up at night to urinate
- •Dry mouth
- •Weight loss
- •Increased blood creatinine levels (seen in lab tests) at the start of treatment
- •Increased blood urea levels (seen in lab tests)
- •Kidney inflammation (tubulointerstitial nephritis)
Important Warnings
- Seek immediate medical help if you experience swelling of your face, tongue, or throat, difficulty swallowing or breathing, or hives. These could be signs of a very rare but severe allergic reaction (angioedema).
- Contact your doctor or nearest hospital right away if you have symptoms like nausea, vomiting, stomach pain, intense thirst, confusion, unusual sleepiness, sweet-smelling breath, or rapid weight loss. These could be signs of a serious condition called diabetic ketoacidosis, even if your blood sugar levels are normal.
- Tell your doctor immediately if you have pain, tenderness, redness, or swelling in your genital or anal area, especially if you also have a fever. These could be signs of a very rare but life-threatening infection called Fournier's gangrene.
- Stop taking this medicine and see your doctor right away if you get a severe urinary tract infection with symptoms like fever, chills, burning when you pee, or back/side pain. Also, tell your doctor if you see blood in your urine.
- Be aware of symptoms of low blood sugar (hypoglycemia) such as shaking, sweating, intense anxiety, fast heartbeat, hunger, headache, changes in vision, mood changes, or confusion, especially if you also take insulin or other diabetes medicines that lower blood sugar. Your doctor will tell you how to manage low blood sugar.
Show 1 more warnings
- Talk to your doctor before taking this medicine if you have type 1 diabetes, severe kidney or liver problems, very high blood sugar with dehydration (feeling very thirsty, dry mouth, urinating less), or if you often get urinary tract infections. Also, inform your doctor if you feel sick with nausea, vomiting, or fever, as this can lead to dehydration.