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Dailiport

Dailiport contains tacrolimus, a medicine that helps your body accept a transplanted organ and prevents it from being rejected.

Form
depotkapseli, kova
Strength
2 mg
Active Ingredient
Tacrolimus monohydrate
Manufacturer
Sandoz A/S

How to Use

Dosage

Your doctor will determine your dose based on your weight and the type of organ transplanted; it is usually 0.10–0.30 mg per kilogram of body weight per day.

Method

Take the capsules by mouth once daily in the mornings, either on an empty stomach or 2–3 hours after a meal, swallowing them whole with a glass of water.

Important

Your doctor will determine your maximum daily dose based on regular blood tests to ensure the medicine works best for you.

Possible Side Effects

COMMON
  • •High blood sugar, diabetes, or high potassium in your blood.
  • •Trouble sleeping.
  • •Shaking or headaches.
  • •High blood pressure.
  • •Liver problems shown in blood tests.
  • •Diarrhea or feeling sick to your stomach (nausea).
  • •Kidney problems.
  • •Changes in blood cell counts (like low or high white blood cells, or changes in red blood cells).
  • •Changes in blood mineral levels (like low magnesium, potassium, calcium or sodium), too much fluid in the body, high uric acid or fat, poor appetite, high blood acidity.
  • •Feeling anxious, confused, or lost, feeling sad, mood changes, nightmares, seeing or hearing things that aren't there (hallucinations), or other mental issues.
  • •Seizures, problems with being awake or aware, tingling or numbness (sometimes painful) in hands/feet, feeling dizzy, trouble writing, or other nerve issues.
  • •Blurred vision, sensitivity to light, or other eye problems.
  • •Ringing in the ears.
  • •Less blood flow to the heart, or a fast heartbeat.
  • •Bleeding, blood clots blocking vessels, or low blood pressure.
  • •Shortness of breath, changes in lung tissue, fluid around the lungs, sore throat, cough, or flu-like symptoms.
  • •Stomach problems like inflammation or ulcers causing pain/diarrhea, stomach bleeding, mouth inflammation/ulcers, fluid in the belly, throwing up, stomach ache, indigestion, constipation, gas, swelling, or loose stools.
  • •Gallbladder problems, yellowing of skin due to liver issues, liver damage or inflammation.
  • •Itching, rash, hair loss, acne, or sweating more than usual.
  • •Joint, arm, leg, back, or foot pain, or muscle cramps.
  • •Kidney failure, less urine, or painful/difficult urination.
  • •General weakness, fever, fluid buildup in the body, pain/discomfort, high alkaline phosphatase in blood, weight gain, or feeling hot or cold unusually.
RARE
  • •Changes in how your blood clots, or low counts of all types of blood cells.
  • •Dehydration or inability to pass urine.
  • •Abnormal blood test results (like low protein or sugar, high phosphate, or high lactate dehydrogenase).
  • •Deep unconsciousness (coma), bleeding in the brain, stroke, paralysis, brain disease, trouble speaking or understanding, or memory problems.
  • •Clouding of the eye lens or hearing problems.
  • •Irregular heartbeat, cardiac arrest, weak heart, heart muscle disease, enlarged heart muscle, stronger heartbeat, abnormal ECG readings, or abnormal heart rate/pulse.
  • •Blood clot in a leg or arm vein, or shock.
  • •Breathing difficulties, airway disease, or asthma.
  • •Blockage in the intestines, high levels of a pancreatic enzyme (amylase) in the blood, stomach contents coming up into the throat, or slow emptying of the stomach.
  • •Skin inflammation or a burning feeling in the sun.
  • •Joint problems.
  • •Painful or unusual menstrual bleeding.
  • •Problems with multiple organs not working well, flu-like symptoms, increased sensitivity to heat/cold, chest pressure, nervousness or unusual sensations, or weight loss.
  • •Small skin bleeds due to blood clots.
  • •Increased muscle stiffness.
  • •Deafness.
  • •Fluid around the heart.
  • •Sudden severe breathing difficulty.
  • •Cysts in the pancreas.
  • •Problems with blood flow in the liver.
  • •Serious skin disease with blisters on the skin, mouth, eyes, and genitals; increased body hair.
  • •Thirst, falls, feeling of pressure in the chest, less ability to move, or sores.
  • •Muscle weakness.
  • •Abnormal heart ultrasound (echocardiogram).
  • •Liver failure.
  • •Painful urination with blood in the urine.
  • •Increased fatty tissue.

Important Warnings

  • Do not take if you are allergic to tacrolimus, sirolimus, certain antibiotics (like erythromycin), peanuts, or soy.
  • Tell your doctor immediately if you have vision problems, such as blurred vision or changes in color vision.
  • Avoid sunlight and UV radiation; use protective clothing and high SPF sunscreen due to an increased risk of skin cancer.
  • This medicine is not recommended for children and adolescents under 18 years.
  • Do not use with ciclosporin or other medicines that may affect Dailiport's effectiveness; ask your doctor.
Show 4 more warnings
  • Avoid grapefruit and grapefruit juice.
  • Do not breastfeed while taking this medicine.
  • Do not drive or operate machinery if you feel dizzy, sleepy, or have vision problems, especially if you have consumed alcohol.
  • Dailiport weakens your immune system against infections, so you might get sick more easily.

Additional Information

ATC Code: L04AD02
→ View Professional Information (PDF)→ View Patient Leaflet (PDF)