Dacarbazine medac
Dacarbazine medac is a type of chemotherapy that works by slowing the growth of cancer cells.
Form
infuusiokuiva-aine, liuosta varten
Strength
1000 mg
Active Ingredient
Dacarbazine
Manufacturer
Medac Gesellschaft Für Klinische Spezialpräparate mbH
How to Use
Dosage
The dose depends on your cancer type and body surface area, typically 200-250 mg per square meter of body surface.
Method
This medicine is given as an infusion into a vein (intravenously) over 20-30 minutes by a doctor or nurse.
Important
Up to 1000 mg per square meter of body surface per dose, given every 3 weeks.
Possible Side Effects
COMMON
- •Low red blood cell count (anemia), low white blood cell count (leukopenia), and/or low platelet count (thrombocytopenia).
- •Loss of appetite, nausea, and vomiting (can be severe).
RARE
- •Hair loss.
- •Increased skin pigmentation.
- •Skin sensitivity to light.
- •Flu-like symptoms (fatigue, chills, fever, muscle pain).
- •Infections.
- •Low count of all blood cells (pancytopenia).
- •Significant decrease in granulocytes (a type of white blood cell), known as agranulocytosis.
- •Severe allergic reaction (anaphylaxis), with symptoms like low blood pressure, swelling (hands, feet, ankles, face, lips, mouth, throat), difficulty swallowing or breathing, rapid pulse, hives, itching, or skin redness.
- •Headache.
- •Blurred vision.
- •Confusion.
- •Weakness or faintness.
- •Seizures (convulsions).
- •Abnormal sensations in the face (numbness, tingling), facial numbness and flushing soon after injection.
- •Diarrhea.
- •Elevated liver enzyme levels.
- •Impaired kidney function.
- •Skin redness (erythema).
- •Sudden rashes (maculopapular exanthema).
- •Hives (urticaria).
- •Irritation at the injection site.
Important Warnings
- Do not take if you are allergic to dacarbazine or any other ingredients in this medicine.
- Do not take if your white blood cell or platelet count is low.
- Do not take if you have severe liver or kidney disease.
- Do not take if you are pregnant or breastfeeding.
- Do not take with yellow fever vaccine or at the same time as fotemustine.
Show 7 more warnings
- Tell your doctor if you are receiving radiation therapy or other chemotherapy, as combining them with dacarbazine can harm your bone marrow.
- Using dacarbazine with methoxypsoralen can make you more sensitive to sunlight.
- Using dacarbazine with phenytoin can increase the chance of seizures.
- Do not receive live vaccines while taking dacarbazine, as it may weaken your immune system and increase infection risk.
- Do not eat right before receiving dacarbazine to reduce nausea or vomiting. Avoid alcohol during chemotherapy.
- Women who can become pregnant and men should use effective contraception during and for a period after treatment.
- This medicine may affect your ability to drive or use machines due to effects on the brain and nerves, or nausea and vomiting.