Dabigatran etexilate Orion
Dabigatran etexilate Orion is a medicine that helps prevent blood clots from forming in your body.
How to Use
Dosage
Take this medicine exactly as your doctor tells you. Doses vary based on what you are treating, your age, weight, and kidney function. For adults preventing clots after surgery, typical doses are 220 mg once daily (two 110 mg capsules), or 150 mg once daily if over 75 or with reduced kidney function. For adults treating or preventing clots due to irregular heartbeat, the typical dose is 300 mg twice daily (two 150 mg capsules), or 220 mg twice daily if over 80 or with other risk factors. For children, your doctor will determine the dose based on weight and age, taken twice daily.
Method
Swallow the capsule whole with a glass of water, with or without food. Do not break, chew, or empty the capsule, as this can increase your risk of bleeding.
The maximum daily dose is usually 300 mg twice daily (600 mg total), but your doctor will tell you your exact maximum dose.
Possible Side Effects
- •Bleeding (like nosebleeds, blood in urine or stool, bruising easily, or bleeding from wounds/cuts)
- •Upset stomach, stomach pain, feeling sick (nausea) or vomiting, heartburn, or diarrhea
- •Lower numbers of red blood cells (anemia), making you feel tired or pale
- •Allergic reactions like a skin rash or itching
- •Changes in how your liver works (seen in blood tests)
- •Serious bleeding (in the brain, from surgery, injection sites, or from a severe injury)
- •Coughing up blood
- •Severe allergic reaction with trouble breathing, dizziness, or swelling of the face and throat
- •Stomach or throat ulcers
- •Difficulty swallowing
- •Yellow skin or eyes (jaundice)
- •Lower numbers of blood platelets, which help stop bleeding
Important Warnings
- Do not take this medicine if you are allergic to dabigatran etexilate or any other ingredient in this medicine.
- Do not take this medicine if you have severe kidney disease or if you are currently bleeding.
- Do not take this medicine if you have a condition that increases your risk of severe bleeding, such as a stomach ulcer, a brain injury, or recent brain or eye surgery.
- Do not take this medicine if you are taking other blood thinning medications, unless specifically instructed by your doctor to switch medications.
- Do not take this medicine if you have severe liver disease, a mechanical heart valve, or if you are taking certain antifungal or antiviral medicines, or medicines for irregular heart rhythm or to prevent organ rejection.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Consider renal impairment, age and body weight when determining the dosage. Consider potential interactions especially with other drugs that increase the risk of bleeding. (updated 19.9.2025)