Coversyl Comp Novum
Coversyl Comp Novum 10 mg/2.5 mg is a combination medicine used to treat high blood pressure by helping to relax blood vessels and increase urine output.
Form
tabletti, kalvopäällysteinen
Strength
10 mg / 2.5 mg
Active Ingredient
Perindopril arginine
Manufacturer
Les Laboratoires Servier
How to Use
Dosage
One tablet once daily.
Method
Take the tablet in the morning before a meal with a glass of water.
Important
Do not take more than one tablet per day.
Possible Side Effects
COMMON
- •Low potassium in the blood
- •Skin reactions in people prone to allergies or asthma
- •Headache
- •Dizziness
- •Vertigo
- •Tingling sensation
- •Vision disturbances
- •Ringing in the ears (tinnitus)
- •Cough
- •Shortness of breath
- •Digestive issues (nausea, vomiting, stomach pain, taste disturbance, indigestion, diarrhea, constipation)
- •Allergic reactions (like rashes, itching)
- •Muscle cramps
- •Fatigue
RARE
- •Mood changes
- •Depression
- •Sleep disturbances
- •Hives (urticaria)
- •Red spots on the skin (purpura)
- •Blister clusters
- •Kidney problems
- •Impotence (inability to get or maintain an erection)
- •Sweating
- •Increased number of eosinophils (a type of white blood cell)
- •Changes in lab values: high potassium in the blood (reverses after stopping treatment), low sodium in the blood (can lead to dehydration and low blood pressure)
- •Drowsiness
- •Fainting
- •Palpitations (awareness of heartbeats)
- •Fast heartbeat (tachycardia)
- •Very low blood sugar (hypoglycemia) in diabetic patients
- •Blood vessel inflammation (vasculitis)
- •Dry mouth
- •Photosensitivity reactions (skin sensitivity to sunlight)
- •Joint pain (arthralgia)
- •Muscle pain (myalgia)
- •Chest pain
- •Feeling unwell
- •Swelling of the extremities
- •Fever
- •Increased blood urea levels
- •Increased blood creatinine levels
- •Falls
- •Worsening of psoriasis
- •Changes in lab values: low chloride, low magnesium, increased liver enzymes, high bilirubin in blood
- •Reduced or no urine output; acute kidney failure
- •Dark urine, nausea or vomiting, muscle cramps, confusion and seizures. These may be symptoms of SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion).
- •Confusion
- •Eosinophilic pneumonia (a rare type of lung inflammation)
- •Runny or stuffy nose
- •Severe kidney problems
- •Changes in blood cell counts, such as decreased white and red blood cells, decreased hemoglobin, decreased platelets
- •High calcium in the blood
- •Abnormal liver function
- •Abnormal heart electrical activity (ECG)
- •Changes in lab values: high uric acid and high blood sugar levels
- •Nearsightedness (myopia); blurred vision; reduced vision, decreased visual acuity or eye pain due to high eye pressure (possible signs of fluid buildup in the choroid or acute angle-closure glaucoma)
- •Color change, numbness, and pain in fingers or toes (Raynaud's phenomenon)
- •Worsening of systemic lupus erythematosus (a connective tissue disease)
Important Warnings
- Do not take if you are allergic to perindopril, indapamide, other ACE inhibitors, sulfonamides, or any other ingredient in this medicine.
- Do not take if you or a family member have had swelling of the face, tongue, or throat (angioedema) in the past, especially with other ACE inhibitor medicines.
- Do not take if you have diabetes or kidney problems and are taking aliskiren for high blood pressure.
- Do not take if you have severe liver disease or a brain disease caused by liver problems (hepatic encephalopathy).
- Do not take if you are more than 3 months pregnant; it is also best to avoid this medicine during early pregnancy as it can harm your baby.
Show 1 more warnings
- Do not take if you are currently taking or have recently taken sacubitril/valsartan (a medicine for heart failure) due to an increased risk of angioedema.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Effectiveness is reduced in renal impairment. Consider risk of orthostatic hypotension and hyponatraemia and -kalemia. (updated 19.5.2025)