Coveram
Coveram tablets are used to treat high blood pressure and/or stable coronary artery disease.
Form
tabletti
Strength
5 mg / 5 mg
Active Ingredient
Perindopril arginine
Manufacturer
Les Laboratoires Servier
How to Use
Dosage
Usually one tablet per day.
Method
Swallow the tablet whole with water, preferably in the morning before a meal.
Important
One tablet per day, unless your doctor advises otherwise.
Possible Side Effects
COMMON
- •Swelling (fluid retention)
- •Headache
- •Dizziness
- •Tiredness (especially at the start of treatment)
- •Vertigo
- •Numbness or tingling sensation
- •Vision problems (including double vision)
- •Tinnitus (ringing in the ears)
- •Palpitations (awareness of heart beat)
- •Flushing
- •Confusion due to low blood pressure
- •Cough
- •Shortness of breath
- •Nausea
- •Vomiting
- •Abdominal pain
- •Taste disturbances
- •Indigestion or digestive problems
- •Changed bowel habits (diarrhea, constipation)
- •Allergic reactions (rash, itching)
- •Muscle cramps
- •Weakness
- •Ankle swelling
RARE
- •Mood changes, anxiety, depression, insomnia
- •Tremor
- •Fainting
- •Loss of pain sensation
- •Irregular heartbeat
- •Rhinitis (blocked or runny nose)
- •Hair loss
- •Red patches on skin, skin discoloration
- •Back pain, muscle or joint pain, chest pain
- •Urination problems (increased need, especially at night)
- •Pain, feeling unwell
- •Asthma attack (wheezing, shortness of breath)
- •Dry mouth
- •Swelling of face or tongue (angioedema)
- •Blisters on the skin
- •Kidney problems
- •Impotence
- •Increased sweating
- •Increased eosinophils (a type of white blood cell)
- •Breast discomfort or breast enlargement in men
- •Weight gain or loss
- •Fast heartbeat
- •Blood vessel inflammation (vasculitis)
- •Photosensitivity (skin sensitivity to sunlight)
- •Fever
- •Falls
- •Changes in lab tests (high potassium, low sodium, low blood sugar in diabetics, high urea and creatinine)
- •Acute kidney failure
- •SIADH symptoms (dark urine, nausea, vomiting, muscle cramps, confusion, seizures)
- •Worsening of psoriasis
- •Changes in lab tests (increased liver enzymes and bilirubin)
- •Heart and circulatory problems (chest pain, heart attack, stroke)
- •Eosinophilic pneumonia
- •Swelling of eyelids, face, lips, tongue or throat (severe breathing difficulties)
- •Severe skin reactions (such as blisters, peeling, Stevens-Johnson syndrome, erythema multiforme, photosensitivity)
- •Blood test changes (low white and red blood cells, hemoglobin, platelets)
- •Pancreatitis (severe stomach and back pain, nausea)
- •Liver problems (inflammation, jaundice, abnormal liver enzymes)
- •Stomach swelling (gastritis)
- •Nerve problems (weakness, tingling, numbness, muscle tension)
- •Gum swelling
- •Too much sugar in the blood (high blood sugar)
- •Stiff posture
- •Mask-like face
- •Slow movements and shuffling, unsteady gait
- •Raynaud's phenomenon (discoloration, numbness and pain in fingers or toes)
Important Warnings
- Do not take Coveram if you are allergic to perindopril, amlodipine, or similar medicines.
- Do not use Coveram if you are more than 3 months pregnant or planning to become pregnant, as it can harm your baby.
- Do not use this medicine if you have had a severe allergic reaction (angioedema) with swelling of the face or tongue.
- If you have diabetes or kidney problems and are taking a blood pressure medicine containing aliskiren, do not take Coveram.
- Do not take Coveram if you have a narrowed heart valve (aortic stenosis) or heart failure after a heart attack.
Show 3 more warnings
- Do not use Coveram if you have very low blood pressure or certain severe kidney problems.
- Coveram is not recommended for children and adolescents.
- Do not use Coveram if you are currently taking a combination medicine containing sacubitril and valsartan for heart failure, as it increases the risk of a severe allergic reaction.
Use in Elderly Patients
Category A
Suitable for older adults. Significant adverse effects include ankle oedema and orthostatic hypotension. Consider potential interactions. Avoid grapefruit. (updated 17.2.2025)