Cohemin
Cohemin is a vitamin B12 medicine that replaces missing B12 in your body, used to prevent and treat B12 deficiency when oral medicines are not enough.
Form
injektioneste, liuos
Strength
1 mg/ml
Active Ingredient
Hydroxocobalamin acetate
Manufacturer
Orion Corporation
How to Use
Dosage
For starting treatment, one ampoule (1 mg) into a muscle every 2-3 days for two weeks, then one ampoule (1 mg) every 3-4 months. For severe nerve problems, the maintenance dose is 1 mg every two weeks for six months.
Method
Cohemin is given as an injection into a muscle by a nurse or doctor.
Important
Your doctor will decide the maximum dose for you. Large single doses of vitamin B12 are not known to be harmful.
Possible Side Effects
RARE
- •Severe allergic reaction (anaphylaxis) which can be life-threatening, with symptoms like low blood pressure, pale skin, and cold sweats.
- •Headache, nerve problems, tremor (shaking).
- •Nausea (feeling sick), vomiting (being sick), diarrhea.
- •Unusual coloring of urine.
- •Allergic skin reactions, local skin swelling, rash, acne-like rash, hives.
- •Fever, dizziness, hot flashes, chills, general discomfort, local reaction at injection site (pain and itching).
- •Low potassium in the blood (hypokalemia) in early B12 treatment for anemia, which can sometimes cause heart rhythm problems.
- •Involuntary muscle movements (like shaking or twitching) have been seen in some children with B12 deficiency after starting B12 treatment. The exact cause is unknown, and B12 deficiency itself can cause similar symptoms.
Important Warnings
- Do not use Cohemin if you are allergic to hydroxocobalamin, injectable vitamin B12, or any other ingredients in this medicine.
- Cohemin contains cobalt. If you are allergic to cobalt, you might get symptoms like redness or itching at the injection site when using B12 vitamin products. Be careful if you have a cobalt allergy.
- Birth control pills can lower B12 levels. The antibiotic chloramphenicol can make B12 treatment less effective. Tell your doctor or pharmacist about all other medicines you are taking.
- If you experience side effects, stop using the medicine and contact your doctor.
Use in Elderly Patients
Category A
Suitable for older adults. (updated 5.6.2023)