Cofact
Cofact replaces missing clotting factors in your blood to stop or prevent bleeding.
Form
injektiokuiva-aine ja liuotin, liuosta varten
Active Ingredient
Human coagulation factor II
Manufacturer
Prothya Biosolutions Netherlands B.V.
How to Use
Dosage
Your doctor, experienced in treating clotting disorders, will determine your dose based on your condition, weight, and the specific clotting factors you need, and their levels in your blood.
Method
Cofact is given into a vein (intravenously). The recommended rate is about 2 ml per minute.
Important
Your doctor will carefully monitor your blood clotting during treatment, as high doses can increase the risk of serious complications like heart attack and blood clots.
Possible Side Effects
COMMON
- •Blood clots
RARE
- •Decrease in blood pressure
- •Hypersensitivity or allergic reactions
- •Heart attack
- •Nausea, vomiting
- •Redness at infusion site
- •Irritation at infusion site
- •Swelling at infusion site
- •Feeling unwell
- •Temporary increase in liver enzyme levels
- •Stroke
- •Dizziness
- •Pulmonary embolism (blood clot in lung)
- •Difficulty breathing
- •Excessive sweating
- •Itchy skin
- •Hives
- •Rash
Important Warnings
- Do not use Cofact if you are allergic to it or any of its ingredients.
- If you have an acquired lack of certain clotting factors, Cofact should only be used for severe bleeding or emergency surgery requiring a quick fix. Otherwise, lowering your other medication or taking vitamin K is usually enough.
- If you take blood thinners (vitamin K blockers), you have a higher risk of blood clots, and Cofact may increase this risk.
- If you have a genetic lack of a specific clotting factor, use a product that contains only that factor, if available.
- Stop the infusion right away if you have an allergic reaction.
Show 3 more warnings
- There is a risk of blood clots, especially if you receive Cofact often.
- The risk of blood clots is higher for people with heart disease, liver disease, newborns, those having or recently had surgery, or those with a history of blood clot problems. Your doctor will check this.
- Always write down the name and batch number of Cofact every time you receive it.