Clefirem
Clefirem is a medicine that helps protect your nervous system by calming down your immune system to treat multiple sclerosis (MS).
Form
tabletti, kalvopäällysteinen
Strength
14 mg
Active Ingredient
Teriflunomide
Manufacturer
Bausch Health Ireland Limited
How to Use
Dosage
The recommended dose is one 14 mg tablet once daily.
Method
Take Clefirem by mouth once a day, at any time, with or without food. Swallow the tablet whole with some water; do not divide, crush, or chew it.
Important
The maximum daily dose is one 14 mg tablet.
Possible Side Effects
COMMON
- •Headache
- •Diarrhea, feeling sick (nausea)
- •Higher liver enzyme levels (shown in blood tests)
- •Hair thinning
- •Pancreatitis (inflammation of the pancreas, causing stomach pain, nausea, or vomiting)
- •Herpes virus infections, such as cold sores or shingles, which can cause blisters, burning, itching, numbness, or pain.
- •Flu-like symptoms, upper respiratory infections (like colds), urinary tract infections, bronchitis, sinusitis, sore throat, stomach flu caused by virus, tooth infection, tonsillitis, or foot fungus.
- •Low red blood cell count (anemia), changes in liver and white blood cell test results, and increased muscle enzymes.
- •Mild allergic reactions
- •Anxiety
- •Numbness, tingling, weakness, or pain in parts of the body, such as the lower back, legs, hands, or fingers.
- •Feeling your heart beat fast (palpitations)
- •Increased blood pressure
- •Vomiting, toothache, pain in the upper stomach
- •Rash, acne
- •Pain in tendons, joints, bones, or muscles (musculoskeletal pain)
- •Needing to urinate more often than usual
- •Heavy periods
- •General pain
- •Lack of energy or feeling weak (asthenia)
- •Weight loss
RARE
- •Severe allergic reactions, such as hives, swelling of the face, lips, or tongue, or sudden difficulty breathing.
- •Severe skin reactions, such as widespread rashes, blisters, fever, or sores in the mouth.
- •Severe infections or sepsis (a life-threatening infection) with symptoms like high fever, shaking, chills, reduced urine, or confusion.
- •Lung inflammation (pneumonitis) with symptoms like difficulty breathing or a persistent cough.
- •Low platelet count in the blood.
- •Increased skin sensitivity, sharp or throbbing nerve pain in arms or legs (peripheral neuropathy).
- •Nail problems.
- •Pain after an injury.
- •Psoriasis.
- •Inflammation of the mouth or lips.
- •Abnormal blood fat levels.
- •Colon inflammation (colitis).
- •Liver inflammation or damage.
- •High blood pressure in the blood vessels of the lungs (pulmonary hypertension).
- •Severe liver disease, which can cause yellow skin or eyes, unusually dark urine, unexplained nausea, vomiting, or stomach pain.
Important Warnings
- If you have liver problems or drink a lot of alcohol, tell your doctor. They will check your liver.
- If you have high blood pressure, tell your doctor. Clefirem can make it higher.
- Tell your doctor if you have an infection or feel sick. Clefirem can make it harder for your body to fight infections.
- If you get bad skin rashes, blisters, or sores, tell your doctor right away.
- Tell your doctor if you have unexplained cough or trouble breathing.
Show 2 more warnings
- If you feel weak, numb, or have pain in your hands or feet, tell your doctor.
- Tell your doctor if you plan to get any vaccinations.