Celebra
Celebra is a medicine that helps reduce pain and swelling caused by arthritis and similar conditions in adults.
Form
kapseli, kova
Strength
100 mg
Active Ingredient
Celecoxib
Manufacturer
Upjohn EESV
How to Use
Dosage
The usual dose is 200 mg per day. This can be one 200 mg capsule once a day, or one 100 mg capsule twice a day. Your doctor may increase this up to a maximum of 400 mg per day if needed.
Method
Take Celebra capsules by mouth. You can take them with or without food, but try to take your dose at the same time each day. If you have trouble swallowing, you can open the capsule and mix its contents with a spoonful of soft food (like applesauce or yogurt) and swallow it right away with water. Do not chew or crush the contents.
Important
Do not take more than 400 mg of Celebra per day.
Possible Side Effects
COMMON
- •High blood pressure (including worsening of existing high blood pressure)
- •Heart attack
- •Swelling in ankles, legs, or hands (fluid retention)
- •Urinary tract infections
- •Shortness of breath
- •Sinus infection/pain, stuffy/runny nose, sore throat, cough, cold/flu-like symptoms
- •Dizziness
- •Trouble sleeping
- •Vomiting
- •Stomach pain
- •Diarrhea
- •Indigestion or heartburn
- •Gas
- •Rash
- •Itching
- •Stiff muscles
- •Difficulty swallowing
- •Headache
- •Nausea (feeling sick)
- •Joint pain
- •Worsening of existing allergies
- •Accident or injury
RARE
- •Stroke
- •Heart failure, feeling your heart beat fast, fast heartbeat
- •Abnormal liver blood test results
- •Abnormal kidney blood test results
- •Anemia (low red blood cells, causing tiredness and shortness of breath)
- •Anxiety, depression, tiredness, drowsiness, tingling or prickling sensation on skin
- •High potassium levels in blood tests (may cause nausea, tiredness, muscle weakness, or palpitations)
- •Blurred or reduced vision, ringing in ears, mouth pain and sores, hearing problems
- •Constipation, burping, stomach inflammation (indigestion, stomach pain, or vomiting), worsening of stomach or intestinal inflammation
- •Leg cramps
- •Raised, itchy rash (hives)
- •Eye inflammation
- •Skin discoloration (bruises)
- •Chest pain (general pain not related to heart)
- •Swelling of face
- •Bleeding ulcers or holes in the stomach, esophagus, or intestines (causing stomach pain, fever, nausea, vomiting, or blocked bowels), dark or black stool, pancreas inflammation (stomach pain), esophagitis
- •Low sodium levels in blood (hyponatremia)
- •Decreased white blood cells (which fight infection) or platelets (increased risk of bleeding or bruising)
- •Muscle coordination problems
- •Confusion, changes in taste
- •Increased sensitivity to light
- •Hair loss
- •Hallucinations
- •Bleeding in the eye
- •Acute reaction that may lead to lung inflammation
- •Irregular heartbeat
- •Flushing or hot flashes
- •Blood clots in lung blood vessels (symptoms include sudden shortness of breath, sharp chest pain when breathing, or fainting)
- •Bleeding in stomach or intestines (may cause bloody stool or bloody vomit), inflammation of small or large intestine
- •Severe liver inflammation (hepatitis) (symptoms may include nausea, diarrhea, yellow skin or eyes, dark urine, pale stools, easy bleeding, itching, or chills)
- •Acute kidney failure
- •Menstrual problems
- •Severe allergic reactions (including life-threatening anaphylactic shock)
- •Severe skin diseases like Stevens-Johnson syndrome, blistering skin inflammation, toxic epidermal necrolysis (skin rash, blistering or peeling), and sudden widespread pustular rash (swollen red skin with small pus-filled blisters)
- •Delayed allergic reaction (symptoms may include rash, facial swelling, fever, swollen lymph nodes, and abnormal lab test results like elevated liver enzymes or increased white blood cells)
- •Life-threatening brain hemorrhage
- •Meningitis (inflammation of membranes around brain and spinal cord)
- •Liver failure, liver damage, and severe liver inflammation (fulminant hepatitis), sometimes leading to death or liver transplant. Symptoms may include nausea, diarrhea, yellow skin or eyes, dark urine, pale stools, easy bleeding, itching, or chills.
- •Liver problems (such as cholestasis and cholestatic hepatitis), with symptoms like discolored stools, nausea, and yellow skin or eyes.
- •Kidney inflammation and other kidney problems (such as nephrotic syndrome and minimal change disease), with symptoms like fluid retention (swelling), foamy urine, tiredness, and loss of appetite.
- •Worsening of epilepsy (possibly more frequent and/or severe seizures)
- •Blockage of an artery or vein in the eye, leading to partial or complete vision loss
- •Vasculitis (inflammation of blood vessels, may cause fever, aches, purplish-red spots on skin)
- •Decrease in red, white blood cells, and platelets (may cause tiredness, easy bruising, increased nosebleeds, and higher risk of infection)
- •Muscle pain and weakness
- •Reduced sense of smell
- •Loss of taste
- •Swelling of face, lips, tongue, or throat, or difficulty swallowing
Important Warnings
- Do not take Celebra if you are allergic to celecoxib, any of its ingredients, or to sulfonamide medicines (like some antibiotics).
- Do not take Celebra if you have had asthma, nasal polyps, a very stuffy nose, or a serious allergic reaction (like an itchy rash, swelling of your face, lips, tongue, or throat, or trouble breathing) after taking aspirin or other NSAID pain relievers.
- Do not take Celebra if you currently have stomach or intestinal ulcers or bleeding.
- Do not take Celebra if you are pregnant, planning to become pregnant, or are breastfeeding. Celebra may make it harder to get pregnant.
- Do not take Celebra if you have severe liver or kidney disease, severe heart failure, or inflammatory bowel diseases (like ulcerative colitis or Crohn's disease).
Show 8 more warnings
- Do not take Celebra if you have or have had a heart attack, stroke, or problems with blood circulation in your heart, brain, or legs (like blockages).
- Tell your doctor if you have had stomach or intestinal ulcers or bleeding in the past.
- Tell your doctor if you are taking blood thinners (like warfarin, apixaban), low-dose aspirin, other NSAIDs (like ibuprofen or diclofenac), or corticosteroids (like prednisone). Do not take other NSAIDs with Celebra.
- Tell your doctor if you smoke, have diabetes, high blood pressure, or high cholesterol. Your doctor may check your blood pressure regularly.
- Tell your doctor if your heart, liver, or kidneys are not working well, or if you have swelling in your ankles or feet (fluid retention) or are dehydrated.
- Celebra can hide symptoms of infection, like fever. If you suspect an infection, tell your doctor.
- Drinking alcohol with NSAIDs, including Celebra, can increase your risk of stomach and intestinal problems.
- Stop taking Celebra and contact your doctor immediately if you notice signs of a severe skin reaction (like a serious rash, blistering, or peeling skin) or severe liver problems (like nausea, diarrhea, yellow skin or eyes, dark urine, pale stools, easy bleeding, itching, or chills).
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. For short-term use only. Consider adverse renal effect in chronic kidney disease. Do not use in severe renal impairment. May increase swelling. Worsens renal and cardiac failure and causes cardiovascular events. Risk of gastrointestinal bleeding less than with traditional NSAIDs. Consider potential interactions especially with preparations that increase risk of bleeding. (updated 16.9.2024)