Carboplatin Accord
Carboplatin Accord is a medicine used to treat certain types of lung and ovarian cancers.
Form
infuusiokonsentraatti, liuosta varten
Strength
10 mg/ml
Active Ingredient
Carboplatin
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will determine the correct dose and how often you should receive it, based on your health, size, and kidney function. Doses are usually given every 4 weeks.
Method
This medicine is given into a vein as a drip (infusion) over 15 to 60 minutes.
Important
Your doctor will determine the appropriate dose for each treatment cycle. There is no specific maximum daily dose as it's typically given every 4 weeks.
Possible Side Effects
COMMON
- •Feeling tired, short of breath, and pale because you have too few red blood cells (anemia). Also, changes in your white blood cells and platelets, which your doctor will check with blood tests.
- •Feeling sick to your stomach, throwing up, stomach pain, or cramps.
- •Diarrhea or constipation.
- •Skin rash and/or itching.
- •Ringing in your ears or changes in hearing.
- •Hair loss.
- •Flu-like symptoms (like feeling unwell) or infections.
- •Tingling, numbness, or burning in hands, feet, arms, or legs, and weaker reflexes.
- •Changes in or loss of taste.
- •Temporary loss or changes in vision.
- •Heart problems, chest tightness, or trouble breathing.
- •Sores on your lips or in your mouth.
- •Pain or discomfort in your bones, joints, or muscles.
- •Kidney or urinary problems. Your doctor will check your kidney function with blood and urine tests.
- •Changes in liver enzyme levels. Your doctor will check your liver function with blood tests.
- •Changes in blood levels of urea, sodium, potassium, calcium, magnesium, or uric acid (which can cause gout).
RARE
- •Skin peeling.
- •Scarring in the lungs, making you short of breath and/or cough.
- •Developing a new cancer caused by the carboplatin treatment.
- •Feeling very sick with a fever due to a severe drop in white blood cells (febrile neutropenia).
- •Bone marrow failure (your body not making enough blood cells).
- •Dry mouth, tiredness, and headache from losing too much fluid.
- •Loss of appetite.
- •Severe liver damage or liver failure.
- •Heart failure.
- •Changes in blood pressure (either too high or too low).
- •Hives, redness, rash, or itching on your skin.
- •Swelling or tenderness where the medicine was injected.
- •Headache, changes in how your mind works, seizures, and vision problems (from blurry vision to blindness), which can be signs of a rare brain disorder.
- •Inflammation of the pancreas (pancreatitis).
- •Lung infection.
- •Brain disease (encephalopathy).
- •Anemia caused by your red blood cells breaking down too fast.
- •Stroke (sudden weakness or numbness in your face, arm, or leg, often on one side).
- •Blood clots in your vessels, and swelling or pain in an arm or leg.
- •Chest pain, which can be a sign of a severe allergic reaction (Kounis syndrome).
- •Swelling of your skin, often on your face and lips.
- •Muscle cramps, muscle weakness, confusion, vision problems, irregular heartbeat, kidney failure, or abnormal blood tests. These are signs of tumor lysis syndrome, caused by fast breakdown of cancer cells.
- •Very tired, short of breath, low red blood cells, low platelets, unusual bruising, and kidney problems with little or no urine. These are signs of hemolytic uremic syndrome.
- •Fever (temperature of at least 38°C) or chills, which could mean you have an infection.
Important Warnings
- Do not use if you are allergic to carboplatin or similar platinum medicines.
- Do not use if you have severe kidney disease.
- Do not use if you have very few blood cells (your doctor will check this with a blood test) or a tumor that is bleeding.
- Do not use if you are about to get or have recently had a yellow fever vaccine.
- Tell your doctor if you are pregnant, might be pregnant, or are breastfeeding.
Show 3 more warnings
- Tell your doctor about all other medicines you are taking, especially those that can affect blood cells, kidneys, hearing, or blood clotting, or if you are on immunosuppressants.
- Do not drive or use machines if you feel sick, dizzy, or have problems with your vision or hearing.
- Women must use effective birth control during treatment and for 6 months after the last dose. Men must use effective birth control during treatment and for 3 months after their last dose.