Calciumfolinate Sandoz
Calciumfolinate Sandoz helps reduce the side effects of certain cancer medications and can also be used to treat overdose.
Form
injektio-/infuusioneste, liuos
Strength
10 mg/ml
Active Ingredient
Calcium folinate
Manufacturer
Sandoz A/S
How to Use
Dosage
Your doctor will determine the dose based on your body surface area, the type of cancer treatment, and other ongoing treatments.
Method
This medicine is given by a doctor or nurse as an injection or infusion into a vein, or as an injection into a muscle.
Important
When given into a vein, calcium folinate should not be injected faster than 160 mg per minute.
Possible Side Effects
COMMON
- •Nausea (when used with fluoropyrimidines)
- •Vomiting (when used with fluoropyrimidines)
- •Severe diarrhea (when used with fluoropyrimidines)
- •Dehydration, possibly due to diarrhea (when used with fluoropyrimidines)
- •Inflammation of the intestinal and oral mucous membranes (mucositis/stomatitis), including life-threatening cases (when used with fluoropyrimidines)
- •Decrease in blood cell count, including life-threatening cases (when used with fluoropyrimidines)
- •Redness and swelling of the palms of the hands and soles of the feet, which may involve skin peeling (hand-foot syndrome) (when used with fluoropyrimidines)
RARE
- •Severe allergic reaction (itchy rash, swelling of hands, feet, ankles, face, lips, mouth or throat, dizziness)
- •Fever
- •Insomnia (difficulty sleeping)
- •Agitation
- •Depression
- •Digestive problems
- •Increased epileptic seizures in patients with epilepsy
- •Elevated blood ammonia levels
Important Warnings
- Do not use if you are allergic to calcium folinate or any other ingredients in this medicine.
- Do not use if you have too few red blood cells (anemia).
- Do not use this medicine with certain cancer drugs (like 5-fluorouracil) if you are pregnant or breastfeeding, as it may harm the baby.
- This medicine must not be given directly into the spinal cord or brain (intrathecally).
- Tell your doctor if you have epilepsy or kidney problems.
Show 2 more warnings
- Always tell your doctor or pharmacist about all other medicines you are taking or have recently taken.
- Do not use this medicine if the solution is cloudy or has particles.