Bupropion Sandoz

Bupropion Sandoz is a medicine used to treat depression by affecting chemicals in your brain.

Form
säädellysti vapauttava tabletti
Strength
150 mg
Active Ingredient
Bupropion hydrochloride
Manufacturer
Sandoz A/S

How to Use

Dosage

The usual dose is one 150 mg tablet once a day. Your doctor may increase the dose to 300 mg once a day if your depression does not improve. If you have mild liver or kidney problems, the dose is usually one 150 mg tablet once a day.

Method

Swallow the tablet whole with water in the morning. You can take it with or without food. Do not chew, crush, or divide the tablet, as this can cause the medicine to be released too quickly.

Important

The maximum daily dose is usually 300 mg once a day, unless your doctor has prescribed otherwise.

Possible Side Effects

COMMON
  • Trouble sleeping
  • Headache
  • Dry mouth
  • Nausea, vomiting
  • Fever, dizziness, itching, sweating, and rash (sometimes due to an allergic reaction)
  • Shaking, trembling, weakness, fatigue, chest pain
  • Anxiety or irritability
  • Stomach pain or other stomach problems (like constipation), changes in taste, loss of appetite
  • Increased blood pressure (sometimes severe), flushing
  • Ringing in ears, vision problems
RARE
  • Depression
  • Feeling confused
  • Lack of concentration
  • Increased heart rate
  • Weight loss
  • Seizure
  • Palpitations, fainting
  • Twitching, muscle stiffness, uncontrolled movements, problems with walking or coordination
  • Restlessness, irritability, hostility, aggression, strange dreams, numbness or tingling, memory problems
  • Yellowing of skin or whites of eyes (may be due to liver inflammation)
  • Severe allergic reactions; rash with joint and muscle pain
  • Changes in blood sugar levels
  • Increased or decreased need to urinate
  • Severe rash in the mouth or other body parts (can be life-threatening)
  • Worsening of psoriasis
  • Feeling unreal or strange (depersonalization); hallucinations or delusions, strong suspicion
  • Low blood sodium levels
  • Suicidal thoughts during or after treatment
  • Loss of touch with reality and difficulty thinking clearly (psychosis); hallucinations and delusions
  • Decrease in red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia)
  • Changes in mental state (e.g., restlessness, hallucinations, coma) and other symptoms, such as high fever, fast heart rate, unstable blood pressure, muscle stiffness, coordination problems, and stomach problems (nausea, vomiting, diarrhea) when this medicine is used with other antidepressants.

Important Warnings

  • Do not take if you are allergic to bupropion or any other ingredients in this medicine.
  • Do not take if you are using other medicines that contain bupropion.
  • Do not take if you have epilepsy or have had seizures before.
  • Do not take if you have a brain tumor.
  • Do not take if you are suddenly stopping alcohol or sedatives (like sleeping pills or muscle relaxants).
Show 10 more warnings
  • Do not take if you have a severe, long-term liver disease.
  • Do not take if you have or have had an eating disorder, like bulimia or anorexia.
  • Do not take if you are using or have used antidepressants called MAOIs. You must wait at least 14 days after stopping MAOIs before taking this medicine.
  • Talk to your doctor if you have Brugada syndrome (a rare heart rhythm disorder) or if sudden heart failure has occurred in your family.
  • If you have thoughts of harming yourself or committing suicide, contact a doctor or go to a hospital immediately.
  • Stop taking the medicine right away and contact your doctor if you have a seizure during treatment.
  • Drinking alcohol is not recommended with this medicine. If you drink a lot, do not stop drinking suddenly, as it can cause seizures. Talk to your doctor about your alcohol use.
  • Do not take if you are pregnant, think you might be pregnant, or are planning to get pregnant, unless your doctor tells you to. If you are breastfeeding, talk to your doctor, as the medicine can pass into breast milk.
  • Do not drive or use machines if this medicine makes you feel confused or dizzy.
  • Also talk to your doctor if you: regularly drink a lot of alcohol, have diabetes and are treated with insulin or tablets, have had a severe head injury, or have extreme mood swings or other mental health issues.

Use in Elderly Patients

Category C

Suitable for older adults, with specific precautions. Consider risk of convulsions and numerous potential interactions. Reduce the dose already in mild renal impairment. Increases risk of falls. (updated 12.2.2024)